Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
132 cases with simple somatic mutation data · 132 cases total · 2026-01-08 · mapped to T-Cell Non-Hodgkin Lymphoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TET2 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 68 |
| 132 |
| 51.5% |
| cbioportal |
| 2 | RHOA | Ssm | 40 | 131 | 30.5% | cbioportal |
| 3 | DNMT3A | Ssm | 25 | 132 | 18.9% | cbioportal |
| 4 | TP53 | Ssm | 21 | 132 | 15.9% | cbioportal |
| 5 | IDH2 | Ssm | 15 | 132 | 11.4% | cbioportal |
| 8 | PLCG1 | Ssm | 8 | 102 | 7.8% | cbioportal |
| 6 | FAT1 | Ssm | 10 | 131 | 7.6% | cbioportal |
| 7 | STAT3 | Ssm | 10 | 131 | 7.6% | cbioportal |
| 9 | SETD2 | Ssm | 8 | 131 | 6.1% | cbioportal |
| 10 | FAS | Ssm | 6 | 102 | 5.9% | cbioportal |
| 12 | POT1 | Ssm | 6 | 102 | 5.9% | cbioportal |
| 16 | VAV1 | Ssm | 5 | 102 | 4.9% | cbioportal |
| 14 | KSR2 | Ssm | 5 | 102 | 4.9% | cbioportal |
| 11 | KMT2D | Ssm | 6 | 131 | 4.6% | cbioportal |
| 29 | TET3 | Ssm | 4 | 102 | 3.9% | cbioportal |
| 27 | ROBO1 | Ssm | 4 | 102 | 3.9% | cbioportal |
| 20 | DDX3X | Ssm | 4 | 102 | 3.9% | cbioportal |
| 15 | STAT5B | Ssm | 5 | 131 | 3.8% | cbioportal |
| 13 | JAK1 | Ssm | 5 | 132 | 3.8% | cbioportal |
| 187 | PTPRT | Ssm | 1 | 29 | 3.4% | cbioportal |
| 168 | NCOA3 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 131 | ERCC2 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 192 | RIT1 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 186 | PTPRS | Ssm | 1 | 29 | 3.4% | cbioportal |
| 148 | H3-4 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 158 | LATS2 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 28 | SOCS1 | Ssm | 4 | 131 | 3.1% | cbioportal |
| 25 | PIK3C2G | Ssm | 4 | 131 | 3.1% | cbioportal |
| 22 | GRIN2A | Ssm | 4 | 131 | 3.1% | cbioportal |
| 30 | TNFAIP3 | Ssm | 4 | 131 | 3.1% | cbioportal |
Data updated 21 days agoSource updated 2026-01-08