Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
66 cases with simple somatic mutation data · 66 cases total · 2026-01-13 · mapped to Cutaneous Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | BRAF |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 66 |
| 66 |
| 100% |
| cbioportal |
| 2 | PTPRT | Ssm | 16 | 66 | 24.2% | cbioportal |
| 3 | KMT2C | Ssm | 14 | 66 | 21.2% | cbioportal |
| 4 | CDKN2A | Ssm | 13 | 66 | 19.7% | cbioportal |
| 5 | GRM3 | Ssm | 13 | 66 | 19.7% | cbioportal |
| 92 | CBLC | Ssm | 2 | 11 | 18.2% | cbioportal |
| 7 | PAK5 | Ssm | 12 | 66 | 18.2% | cbioportal |
| 6 | NOTCH4 | Ssm | 12 | 66 | 18.2% | cbioportal |
| 116 | MAP3K1 | Ssm | 2 | 11 | 18.2% | cbioportal |
| 10 | PTEN | Ssm | 11 | 66 | 16.7% | cbioportal |
| 9 | PREX2 | Ssm | 11 | 66 | 16.7% | cbioportal |
| 8 | GRIN2A | Ssm | 11 | 66 | 16.7% | cbioportal |
| 12 | TP53 | Ssm | 10 | 66 | 15.2% | cbioportal |
| 11 | PTPRD | Ssm | 10 | 66 | 15.2% | cbioportal |
| 13 | EPHA6 | Ssm | 9 | 66 | 13.6% | cbioportal |
| 14 | MAGI2 | Ssm | 9 | 66 | 13.6% | cbioportal |
| 15 | SMARCA4 | Ssm | 9 | 66 | 13.6% | cbioportal |
| 17 | KMT2D | Ssm | 8 | 66 | 12.1% | cbioportal |
| 19 | TERT | Ssm | 8 | 66 | 12.1% | cbioportal |
| 16 | ATM | Ssm | 8 | 66 | 12.1% | cbioportal |
| 18 | ROS1 | Ssm | 8 | 66 | 12.1% | cbioportal |
| 20 | AR | Ssm | 7 | 66 | 10.6% | cbioportal |
| 25 | PIK3C2G | Ssm | 7 | 66 | 10.6% | cbioportal |
| 24 | FAT1 | Ssm | 7 | 66 | 10.6% | cbioportal |
| 23 | EPHA7 | Ssm | 7 | 66 | 10.6% | cbioportal |
| 22 | EPHA10 | Ssm | 7 | 66 | 10.6% | cbioportal |
| 21 | CARD11 | Ssm | 7 | 66 | 10.6% | cbioportal |
| 29 | NOTCH3 | Ssm | 6 | 66 | 9.1% | cbioportal |
| 198 | SMAD3 | Ssm | 1 | 11 | 9.1% | cbioportal |
| 28 | IL7R | Ssm | 6 | 66 | 9.1% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13