Gene
TET3
tet methylcytosine dioxygenase 3
Explore in graph →CI-GENE-00034924HGNC:28313 ENSG00000187605 NCBI 200424 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25589618
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cutaneous Squamous Cell Carcinoma (DFCI, Clin Cancer Res 2015) cscc_dfarber_2015 | Skin Squamous Cell Carcinoma | Ssm | 5 | 29 | 17.2% | 92 | cbioportal |
| Upper Tract Urothelial Carcinoma (Cornell/Baylor/MDACC, Nat Commun 2019) utuc_cornell_baylor_mdacc_2019 | Renal Pelvis and Ureter Urothelial Carcinoma | Ssm | 3 | 37 | 8.1% | 88 | cbioportal |
| Mature T and NK Neoplasms (MSK, Blood Adv 2023) mtnn_msk_2022 | T-Cell Non-Hodgkin Lymphoma | Ssm | 4 | 102 | 3.9% | 29 | cbioportal |
| China Pan-cancer (OrigiMed, Nature 2022) pan_origimed_2020 | unmapped | Ssm | 209 | 10,194 | 2.1% | 116 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.