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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
90 cases with simple somatic mutation data · 90 cases total · 2026-01-05 · mapped to Bladder Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TERT | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 71 |
| 90 |
| 78.9% |
| cbioportal |
| 2 | FGFR3 | Ssm | 35 | 90 | 38.9% | cbioportal |
| 3 | KDM6A | Ssm | 35 | 90 | 38.9% | cbioportal |
| 4 | TP53 | Ssm | 34 | 90 | 37.8% | cbioportal |
| 24 | USP8 | Ssm | 12 | 34 | 35.3% | cbioportal |
| 5 | KMT2D | Ssm | 31 | 90 | 34.4% | cbioportal |
| 28 | HLA-B | Ssm | 11 | 46 | 23.9% | cbioportal |
| 58 | SERPINB3 | Ssm | 8 | 34 | 23.5% | cbioportal |
| 6 | MDC1 | Ssm | 21 | 90 | 23.3% | cbioportal |
| 7 | ARID1A | Ssm | 20 | 90 | 22.2% | cbioportal |
| 8 | KMT2C | Ssm | 19 | 90 | 21.1% | cbioportal |
| 10 | PIK3CA | Ssm | 18 | 90 | 20% | cbioportal |
| 9 | CREBBP | Ssm | 18 | 90 | 20% | cbioportal |
| 11 | TSC1 | Ssm | 18 | 90 | 20% | cbioportal |
| 12 | ZFHX3 | Ssm | 17 | 88 | 19.3% | cbioportal |
| 13 | ATM | Ssm | 16 | 90 | 17.8% | cbioportal |
| 102 | SERPINB4 | Ssm | 6 | 34 | 17.6% | cbioportal |
| 74 | ATXN7 | Ssm | 6 | 34 | 17.6% | cbioportal |
| 14 | BRCA2 | Ssm | 15 | 90 | 16.7% | cbioportal |
| 15 | ATR | Ssm | 14 | 90 | 15.6% | cbioportal |
| 16 | SPEN | Ssm | 14 | 90 | 15.6% | cbioportal |
| 71 | PREX2 | Ssm | 7 | 46 | 15.2% | cbioportal |
| 112 | HLA-C | Ssm | 5 | 34 | 14.7% | cbioportal |
| 126 | SMARCA2 | Ssm | 5 | 34 | 14.7% | cbioportal |
| 17 | STAG2 | Ssm | 13 | 90 | 14.4% | cbioportal |
| 20 | NF1 | Ssm | 12 | 90 | 13.3% | cbioportal |
| 23 | ROS1 | Ssm | 12 | 90 | 13.3% | cbioportal |
| 18 | ERBB2 | Ssm | 12 | 90 | 13.3% | cbioportal |
| 22 | PALB2 | Ssm | 12 | 90 | 13.3% | cbioportal |
| 19 | FAT1 | Ssm | 12 | 90 | 13.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-05