Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
173 cases with simple somatic mutation data · 186 cases total · 2026-01-13 · mapped to Pancreatic Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KRAS | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 107 |
| 173 |
| 61.8% |
| cbioportal |
| 2 | TP53 | Ssm | 100 | 173 | 57.8% | cbioportal |
| 3 | SMAD4 | Ssm | 36 | 173 | 20.8% | cbioportal |
| 4 | CDKN2A | Ssm | 30 | 173 | 17.3% | cbioportal |
| 5 | TTN | Ssm | 25 | 173 | 14.5% | cbioportal |
| 6 | MUC16 | Ssm | 12 | 173 | 6.9% | cbioportal |
| 7 | RNF43 | Ssm | 11 | 173 | 6.4% | cbioportal |
| 11 | TGFBR2 | Ssm | 8 | 173 | 4.6% | cbioportal |
| 10 | RYR1 | Ssm | 8 | 173 | 4.6% | cbioportal |
| 9 | HECW2 | Ssm | 8 | 173 | 4.6% | cbioportal |
| 8 | ARID1A | Ssm | 8 | 173 | 4.6% | cbioportal |
| 15 | GLI3 | Ssm | 7 | 173 | 4% | cbioportal |
| 16 | GNAS | Ssm | 7 | 173 | 4% | cbioportal |
| 19 | PCDH15 | Ssm | 7 | 173 | 4% | cbioportal |
| 14 | FAT2 | Ssm | 7 | 173 | 4% | cbioportal |
| 21 | TPO | Ssm | 7 | 173 | 4% | cbioportal |
| 13 | CACNA1B | Ssm | 7 | 173 | 4% | cbioportal |
| 18 | LRP1B | Ssm | 7 | 173 | 4% | cbioportal |
| 20 | RNF213 | Ssm | 7 | 173 | 4% | cbioportal |
| 17 | KDM6A | Ssm | 7 | 173 | 4% | cbioportal |
| 12 | ATM | Ssm | 7 | 173 | 4% | cbioportal |
| 25 | COL11A1 | Ssm | 6 | 173 | 3.5% | cbioportal |
| 31 | KCNA6 | Ssm | 6 | 173 | 3.5% | cbioportal |
| 26 | COL5A1 | Ssm | 6 | 173 | 3.5% | cbioportal |
| 27 | COL6A2 | Ssm | 6 | 173 | 3.5% | cbioportal |
| 30 | FLNC | Ssm | 6 | 173 | 3.5% | cbioportal |
| 29 | FLG | Ssm | 6 | 173 | 3.5% | cbioportal |
| 28 | FBN3 | Ssm | 6 | 173 | 3.5% | cbioportal |
| 24 | APBA2 | Ssm | 6 | 173 | 3.5% | cbioportal |
| 42 | RREB1 | Ssm | 6 | 173 | 3.5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13