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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
243 cases with simple somatic mutation data · 243 cases total · 2026-01-07 · mapped to Hepatocellular Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TERT |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 139 |
| 243 |
| 57.2% |
| cbioportal |
| 2 | CTNNB1 | Ssm | 88 | 243 | 36.2% | cbioportal |
| 3 | TP53 | Ssm | 54 | 243 | 22.2% | cbioportal |
| 4 | TTN | Ssm | 52 | 243 | 21.4% | cbioportal |
| 5 | MUC16 | Ssm | 28 | 243 | 11.5% | cbioportal |
| 6 | ALB | Ssm | 27 | 243 | 11.1% | cbioportal |
| 7 | ARID1A | Ssm | 24 | 243 | 9.9% | cbioportal |
| 8 | APOB | Ssm | 22 | 243 | 9.1% | cbioportal |
| 9 | AXIN1 | Ssm | 21 | 243 | 8.6% | cbioportal |
| 10 | PCLO | Ssm | 21 | 243 | 8.6% | cbioportal |
| 12 | RYR2 | Ssm | 20 | 243 | 8.2% | cbioportal |
| 11 | CSMD1 | Ssm | 20 | 243 | 8.2% | cbioportal |
| 13 | OBSCN | Ssm | 19 | 243 | 7.8% | cbioportal |
| 14 | COL11A1 | Ssm | 18 | 243 | 7.4% | cbioportal |
| 15 | DNAH7 | Ssm | 16 | 243 | 6.6% | cbioportal |
| 19 | PCDH15 | Ssm | 15 | 243 | 6.2% | cbioportal |
| 16 | ARID2 | Ssm | 15 | 243 | 6.2% | cbioportal |
| 18 | FBN2 | Ssm | 15 | 243 | 6.2% | cbioportal |
| 17 | CSMD3 | Ssm | 15 | 243 | 6.2% | cbioportal |
| 20 | RPS6KA3 | Ssm | 15 | 243 | 6.2% | cbioportal |
| 24 | NFE2L2 | Ssm | 14 | 243 | 5.8% | cbioportal |
| 22 | KMT2D | Ssm | 14 | 243 | 5.8% | cbioportal |
| 23 | LRP1B | Ssm | 14 | 243 | 5.8% | cbioportal |
| 26 | SPTA1 | Ssm | 14 | 243 | 5.8% | cbioportal |
| 25 | RYR1 | Ssm | 14 | 243 | 5.8% | cbioportal |
| 27 | USH2A | Ssm | 14 | 243 | 5.8% | cbioportal |
| 21 | DNAH9 | Ssm | 14 | 243 | 5.8% | cbioportal |
| 28 | FRAS1 | Ssm | 13 | 243 | 5.3% | cbioportal |
| 29 | ATM | Ssm | 12 | 243 | 4.9% | cbioportal |
| 32 | MAP1B | Ssm | 12 | 243 | 4.9% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07