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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
40 cases with simple somatic mutation data · 40 cases total · 2026-01-06 · mapped to Cholangiocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | BAP1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 8 |
| 40 |
| 20% |
| cbioportal |
| 2 | TP53 | Ssm | 8 | 40 | 20% | cbioportal |
| 3 | PBRM1 | Ssm | 7 | 40 | 17.5% | cbioportal |
| 4 | ARID1A | Ssm | 6 | 40 | 15% | cbioportal |
| 6 | IDH1 | Ssm | 4 | 40 | 10% | cbioportal |
| 5 | FGFR2 | Ssm | 4 | 40 | 10% | cbioportal |
| 7 | TTN | Ssm | 4 | 40 | 10% | cbioportal |
| 18 | PIK3CA | Ssm | 3 | 40 | 7.5% | cbioportal |
| 10 | DNAH11 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 11 | DNAH6 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 9 | CSMD3 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 14 | FAT1 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 17 | NIPBL | Ssm | 3 | 40 | 7.5% | cbioportal |
| 20 | UBE2O | Ssm | 3 | 40 | 7.5% | cbioportal |
| 15 | FAT4 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 16 | HRNR | Ssm | 3 | 40 | 7.5% | cbioportal |
| 19 | SORCS3 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 12 | DNAH9 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 8 | CSMD1 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 13 | EPHA2 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 53 | HMCN1 | Ssm | 2 | 40 | 5% | cbioportal |
| 54 | ICE1 | Ssm | 2 | 40 | 5% | cbioportal |
| 55 | IDH2 | Ssm | 2 | 40 | 5% | cbioportal |
| 56 | IKZF3 | Ssm | 2 | 40 | 5% | cbioportal |
| 57 | IL12RB2 | Ssm | 2 | 40 | 5% | cbioportal |
| 58 | IMPG2 | Ssm | 2 | 40 | 5% | cbioportal |
| 59 | JUN | Ssm | 2 | 40 | 5% | cbioportal |
| 60 | KIF5B | Ssm | 2 | 40 | 5% | cbioportal |
| 61 | KIRREL2 | Ssm | 2 | 40 | 5% | cbioportal |
| 62 | KMT2C | Ssm | 2 | 40 | 5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-06