Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
150 cases with simple somatic mutation data · 186 cases total · 2026-01-12 · mapped to Pancreatic Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KRAS | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 136 |
| 150 |
| 90.7% |
| cbioportal |
| 2 | TP53 | Ssm | 104 | 150 | 69.3% | cbioportal |
| 3 | SMAD4 | Ssm | 37 | 150 | 24.7% | cbioportal |
| 4 | TTN | Ssm | 35 | 150 | 23.3% | cbioportal |
| 5 | CDKN2A | Ssm | 22 | 150 | 14.7% | cbioportal |
| 8 | RYR1 | Ssm | 11 | 150 | 7.3% | cbioportal |
| 7 | OBSCN | Ssm | 11 | 150 | 7.3% | cbioportal |
| 6 | MUC16 | Ssm | 11 | 150 | 7.3% | cbioportal |
| 10 | FLG | Ssm | 10 | 150 | 6.7% | cbioportal |
| 11 | GNAS | Ssm | 10 | 150 | 6.7% | cbioportal |
| 9 | FAT2 | Ssm | 10 | 150 | 6.7% | cbioportal |
| 20 | USH2A | Ssm | 9 | 150 | 6% | cbioportal |
| 13 | CSMD2 | Ssm | 9 | 150 | 6% | cbioportal |
| 17 | LRP1B | Ssm | 9 | 150 | 6% | cbioportal |
| 19 | RNF43 | Ssm | 9 | 150 | 6% | cbioportal |
| 14 | FAT3 | Ssm | 9 | 150 | 6% | cbioportal |
| 15 | FAT4 | Ssm | 9 | 150 | 6% | cbioportal |
| 12 | ADAMTS16 | Ssm | 9 | 150 | 6% | cbioportal |
| 18 | MYO18B | Ssm | 9 | 150 | 6% | cbioportal |
| 16 | HMCN1 | Ssm | 9 | 150 | 6% | cbioportal |
| 22 | ARID1A | Ssm | 8 | 150 | 5.3% | cbioportal |
| 29 | SCN5A | Ssm | 8 | 150 | 5.3% | cbioportal |
| 23 | CACNA1B | Ssm | 8 | 150 | 5.3% | cbioportal |
| 28 | RYR3 | Ssm | 8 | 150 | 5.3% | cbioportal |
| 25 | HECW2 | Ssm | 8 | 150 | 5.3% | cbioportal |
| 30 | TGFBR2 | Ssm | 8 | 150 | 5.3% | cbioportal |
| 27 | RREB1 | Ssm | 8 | 150 | 5.3% | cbioportal |
| 24 | GLI3 | Ssm | 8 | 150 | 5.3% | cbioportal |
| 21 | ADAMTS12 | Ssm | 8 | 150 | 5.3% | cbioportal |
| 26 | PLEC | Ssm | 8 | 150 | 5.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-12