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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
106 cases with simple somatic mutation data · 110 cases total · 2026-01-06 · mapped to Colon Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | APC |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 79 |
| 106 |
| 74.5% |
| cbioportal |
| 2 | TTN | Ssm | 58 | 106 | 54.7% | cbioportal |
| 3 | TP53 | Ssm | 56 | 106 | 52.8% | cbioportal |
| 4 | MUC16 | Ssm | 39 | 106 | 36.8% | cbioportal |
| 5 | KRAS | Ssm | 35 | 106 | 33% | cbioportal |
| 6 | OBSCN | Ssm | 29 | 106 | 27.4% | cbioportal |
| 7 | SYNE1 | Ssm | 28 | 106 | 26.4% | cbioportal |
| 8 | DNAH5 | Ssm | 27 | 106 | 25.5% | cbioportal |
| 9 | FAT3 | Ssm | 27 | 106 | 25.5% | cbioportal |
| 10 | CSMD3 | Ssm | 26 | 106 | 24.5% | cbioportal |
| 11 | FAT4 | Ssm | 26 | 106 | 24.5% | cbioportal |
| 12 | MUC5B | Ssm | 26 | 106 | 24.5% | cbioportal |
| 13 | RYR1 | Ssm | 25 | 106 | 23.6% | cbioportal |
| 15 | ZNF469 | Ssm | 24 | 106 | 22.6% | cbioportal |
| 14 | PCLO | Ssm | 24 | 106 | 22.6% | cbioportal |
| 20 | PLEC | Ssm | 23 | 106 | 21.7% | cbioportal |
| 19 | PIK3CA | Ssm | 23 | 106 | 21.7% | cbioportal |
| 18 | HMCN1 | Ssm | 23 | 106 | 21.7% | cbioportal |
| 17 | COL5A1 | Ssm | 23 | 106 | 21.7% | cbioportal |
| 16 | ACVR2A | Ssm | 23 | 106 | 21.7% | cbioportal |
| 22 | FSIP2 | Ssm | 22 | 106 | 20.8% | cbioportal |
| 21 | ARID1A | Ssm | 22 | 106 | 20.8% | cbioportal |
| 23 | AHNAK2 | Ssm | 21 | 106 | 19.8% | cbioportal |
| 27 | TCF7L2 | Ssm | 21 | 106 | 19.8% | cbioportal |
| 24 | HERC2 | Ssm | 21 | 106 | 19.8% | cbioportal |
| 26 | RYR2 | Ssm | 21 | 106 | 19.8% | cbioportal |
| 25 | NBEA | Ssm | 21 | 106 | 19.8% | cbioportal |
| 28 | DMD | Ssm | 20 | 106 | 18.9% | cbioportal |
| 30 | MUC4 | Ssm | 20 | 106 | 18.9% | cbioportal |
| 29 | DOCK3 | Ssm | 20 | 106 | 18.9% | cbioportal |
Data updated 21 days agoSource updated 2026-01-06