Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
242 cases with simple somatic mutation data · 347 cases total · 2026-02-11 · mapped to Bladder Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TTN |
| Ssm |
| 128 |
| 242 |
| 52.9% |
| cbioportal |
| 2 | TP53 | Ssm | 123 | 242 | 50.8% | cbioportal |
| 3 | MUC16 | Ssm | 80 | 242 | 33.1% | cbioportal |
| 4 | KMT2D | Ssm | 70 | 242 | 28.9% | cbioportal |
| 5 | ARID1A | Ssm | 64 | 242 | 26.4% | cbioportal |
| 6 | OBSCN | Ssm | 61 | 242 | 25.2% | cbioportal |
| 7 | SYNE1 | Ssm | 55 | 242 | 22.7% | cbioportal |
| 8 | MACF1 | Ssm | 54 | 242 | 22.3% | cbioportal |
| 9 | KDM6A | Ssm | 52 | 242 | 21.5% | cbioportal |
| 11 | PIK3CA | Ssm | 46 | 242 | 19% | cbioportal |
| 10 | FAT1 | Ssm | 46 | 242 | 19% | cbioportal |
| 12 | RYR3 | Ssm | 45 | 242 | 18.6% | cbioportal |
| 13 | LRTM3 | Ssm | 44 | 242 | 18.2% | cbioportal |
| 14 | LRP1B | Ssm | 43 | 242 | 17.8% | cbioportal |
| 15 | RNF213 | Ssm | 43 | 242 | 17.8% | cbioportal |
| 16 | FGFR3 | Ssm | 42 | 242 | 17.4% | cbioportal |
| 17 | ADGRV1 | Ssm | 41 | 242 | 16.9% | cbioportal |
| 21 | PKHD1L1 | Ssm | 40 | 242 | 16.5% | cbioportal |
| 18 | CREBBP | Ssm | 40 | 242 | 16.5% | cbioportal |
| 20 | FLG | Ssm | 40 | 242 | 16.5% | cbioportal |
| 19 | DST | Ssm | 40 | 242 | 16.5% | cbioportal |
| 22 | AHNAK2 | Ssm | 39 | 242 | 16.1% | cbioportal |
| 26 | MUC5AC | Ssm | 39 | 242 | 16.1% | cbioportal |
| 27 | PCLO | Ssm | 39 | 242 | 16.1% | cbioportal |
| 25 | HMCN1 | Ssm | 39 | 242 | 16.1% | cbioportal |
| 24 | FAT4 | Ssm | 39 | 242 | 16.1% | cbioportal |
| 23 | ELF3 | Ssm | 39 | 242 | 16.1% | cbioportal |
| 30 | RYR2 | Ssm | 38 | 242 | 15.7% | cbioportal |
| 31 | WIZ | Ssm | 38 | 242 | 15.7% | cbioportal |
| 32 | XIRP2 | Ssm | 38 | 242 | 15.7% | cbioportal |
Data updated 21 days agoSource updated 2026-02-11