Other
Neoplasm by Site
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Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
759 cases with simple somatic mutation data · 826 cases total · Data Release 46.0 · mapped to Acute Myeloid Leukemia CURATED_BROADER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 | DNMT3A | Ssm | 33 | 759 | 4.3% | gdc |
| 2 | NPM1 | Ssm | 32 | 759 | 4.2% | gdc |
| 3 | FLT3 | Ssm | 22 | 759 | 2.9% | gdc |
| 4 | NRAS | Ssm | 20 | 759 | 2.6% | gdc |
| 6 | TP53 | Ssm | 19 | 759 | 2.5% | gdc |
| 7 | TET2 | Ssm | 19 | 759 | 2.5% | gdc |
| 5 | IDH1 | Ssm | 19 | 759 | 2.5% | gdc |
| 8 | RUNX1 | Ssm | 18 | 759 | 2.4% | gdc |
| 10 | CEBPA | Ssm | 15 | 759 | 2% | gdc |
| 9 | WT1 | Ssm | 15 | 759 | 2% | gdc |
| 11 | SRSF2 | Ssm | 14 | 759 | 1.8% | gdc |
| 12 | IDH2 | Ssm | 12 | 759 | 1.6% | gdc |
| 13 | STAG2 | Ssm | 11 | 759 | 1.4% | gdc |
| 14 | BCOR | Ssm | 10 | 759 | 1.3% | gdc |
| 16 | TTN | Ssm | 10 | 759 | 1.3% | gdc |
| 15 | GATA2 | Ssm | 10 | 759 | 1.3% | gdc |
| 17 | PTPN11 | Ssm | 9 | 759 | 1.2% | gdc |
| 19 | DNAH9 | Ssm | 8 | 759 | 1.1% | gdc |
| 18 | EZH2 | Ssm | 8 | 759 | 1.1% | gdc |
| 20 | RAD21 | Ssm | 7 | 759 | 0.9% | gdc |
| 21 | ASXL1 | Ssm | 7 | 759 | 0.9% | gdc |
| 22 | SF3B1 | Ssm | 7 | 759 | 0.9% | gdc |
| 24 | MUC16 | Ssm | 6 | 759 | 0.8% | gdc |
| 28 | PKD1L2 | Ssm | 6 | 759 | 0.8% | gdc |
| 25 | SMC3 | Ssm | 6 | 759 | 0.8% | gdc |
| 26 | HYDIN | Ssm | 6 | 759 | 0.8% | gdc |
| 27 | RYR1 | Ssm | 6 | 759 | 0.8% | gdc |
| 23 | CSF3R | Ssm | 6 | 759 | 0.8% | gdc |
| 31 | SRCAP | Ssm | 5 | 759 | 0.7% | gdc |
| 41 | PHF6 | Ssm | 5 | 759 | 0.7% | gdc |
Data updated 22 days agoSource updated Data Release 46.0