Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
91 cases with simple somatic mutation data · 206 cases total · 2026-02-19 · mapped to Diffuse Glioma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 31 |
| 91 |
| 34.1% |
| cbioportal |
| 2 | PTEN | Ssm | 29 | 91 | 31.9% | cbioportal |
| 3 | EGFR | Ssm | 15 | 91 | 16.5% | cbioportal |
| 4 | NF1 | Ssm | 13 | 91 | 14.3% | cbioportal |
| 5 | PIK3R1 | Ssm | 9 | 91 | 9.9% | cbioportal |
| 6 | RB1 | Ssm | 9 | 91 | 9.9% | cbioportal |
| 7 | ERBB2 | Ssm | 7 | 91 | 7.7% | cbioportal |
| 8 | PIK3CA | Ssm | 6 | 91 | 6.6% | cbioportal |
| 9 | BCL11A | Ssm | 4 | 91 | 4.4% | cbioportal |
| 10 | CHEK2 | Ssm | 4 | 91 | 4.4% | cbioportal |
| 11 | MSH6 | Ssm | 4 | 91 | 4.4% | cbioportal |
| 12 | BRCA2 | Ssm | 3 | 91 | 3.3% | cbioportal |
| 13 | CDKN2A | Ssm | 3 | 91 | 3.3% | cbioportal |
| 20 | TNK2 | Ssm | 3 | 91 | 3.3% | cbioportal |
| 18 | KMT2B | Ssm | 3 | 91 | 3.3% | cbioportal |
| 17 | ITGB3 | Ssm | 3 | 91 | 3.3% | cbioportal |
| 16 | FN1 | Ssm | 3 | 91 | 3.3% | cbioportal |
| 19 | TNC | Ssm | 3 | 91 | 3.3% | cbioportal |
| 15 | EP300 | Ssm | 3 | 91 | 3.3% | cbioportal |
| 14 | DST | Ssm | 3 | 91 | 3.3% | cbioportal |
| 21 | A2M | Ssm | 2 | 91 | 2.2% | cbioportal |
| 22 | ABCC4 | Ssm | 2 | 91 | 2.2% | cbioportal |
| 23 | ADAMTSL3 | Ssm | 2 | 91 | 2.2% | cbioportal |
| 24 | ADGRB3 | Ssm | 2 | 91 | 2.2% | cbioportal |
| 25 | AGAP2 | Ssm | 2 | 91 | 2.2% | cbioportal |
| 26 | BCAR1 | Ssm | 2 | 91 | 2.2% | cbioportal |
| 27 | BCR | Ssm | 2 | 91 | 2.2% | cbioportal |
| 28 | CENPF | Ssm | 2 | 91 | 2.2% | cbioportal |
| 29 | CHAT | Ssm | 2 | 91 | 2.2% | cbioportal |
| 30 | COL1A1 | Ssm | 2 | 91 | 2.2% | cbioportal |
Data updated 21 days agoSource updated 2026-02-19