Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
1,013 cases with simple somatic mutation data · 1,013 cases total · 2026-01-16 · mapped to Prostate Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 189 |
| 1,013 |
| 18.7% |
| cbioportal |
| 2 | TTN | Ssm | 151 | 1,013 | 14.9% | cbioportal |
| 3 | MUC16 | Ssm | 113 | 1,013 | 11.2% | cbioportal |
| 4 | SPOP | Ssm | 92 | 1,013 | 9.1% | cbioportal |
| 5 | SYNE1 | Ssm | 73 | 1,013 | 7.2% | cbioportal |
| 6 | FOXA1 | Ssm | 69 | 1,013 | 6.8% | cbioportal |
| 7 | KMT2C | Ssm | 66 | 1,013 | 6.5% | cbioportal |
| 8 | KMT2D | Ssm | 65 | 1,013 | 6.4% | cbioportal |
| 9 | CSMD3 | Ssm | 61 | 1,013 | 6% | cbioportal |
| 10 | HMCN1 | Ssm | 55 | 1,013 | 5.4% | cbioportal |
| 11 | LRP1B | Ssm | 54 | 1,013 | 5.3% | cbioportal |
| 12 | OBSCN | Ssm | 53 | 1,013 | 5.2% | cbioportal |
| 13 | AR | Ssm | 48 | 1,013 | 4.7% | cbioportal |
| 14 | SPTA1 | Ssm | 47 | 1,013 | 4.6% | cbioportal |
| 15 | USH2A | Ssm | 46 | 1,013 | 4.5% | cbioportal |
| 16 | RYR1 | Ssm | 45 | 1,013 | 4.4% | cbioportal |
| 17 | PTEN | Ssm | 44 | 1,013 | 4.3% | cbioportal |
| 18 | RYR2 | Ssm | 44 | 1,013 | 4.3% | cbioportal |
| 19 | ABCA13 | Ssm | 43 | 1,013 | 4.2% | cbioportal |
| 20 | FAT3 | Ssm | 41 | 1,013 | 4% | cbioportal |
| 21 | ZFHX3 | Ssm | 41 | 1,013 | 4% | cbioportal |
| 22 | DCHS2 | Ssm | 40 | 1,013 | 3.9% | cbioportal |
| 23 | FAT4 | Ssm | 39 | 1,013 | 3.8% | cbioportal |
| 24 | ATM | Ssm | 38 | 1,013 | 3.8% | cbioportal |
| 26 | CSMD1 | Ssm | 37 | 1,013 | 3.7% | cbioportal |
| 25 | CACNA1E | Ssm | 37 | 1,013 | 3.7% | cbioportal |
| 27 | DNAH3 | Ssm | 36 | 1,013 | 3.6% | cbioportal |
| 30 | XIRP2 | Ssm | 34 | 1,013 | 3.4% | cbioportal |
| 29 | MYO15A | Ssm | 34 | 1,013 | 3.4% | cbioportal |
| 28 | MUC4 | Ssm | 34 | 1,013 | 3.4% | cbioportal |
Data updated 21 days agoSource updated 2026-01-16