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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
105 cases with simple somatic mutation data · 106 cases total · 2026-01-07 · mapped to Diffuse Glioma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | MUC16 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 60 |
| 105 |
| 57.1% |
| cbioportal |
| 2 | MUC4 | Ssm | 54 | 105 | 51.4% | cbioportal |
| 3 | MUC6 | Ssm | 52 | 105 | 49.5% | cbioportal |
| 4 | TTN | Ssm | 48 | 105 | 45.7% | cbioportal |
| 5 | TAS2R46 | Ssm | 46 | 105 | 43.8% | cbioportal |
| 6 | PABPC3 | Ssm | 44 | 105 | 41.9% | cbioportal |
| 7 | MUC2 | Ssm | 43 | 105 | 41% | cbioportal |
| 8 | TRBV7-7 | Ssm | 43 | 105 | 41% | cbioportal |
| 9 | GXYLT1 | Ssm | 42 | 105 | 40% | cbioportal |
| 11 | PLIN4 | Ssm | 40 | 105 | 38.1% | cbioportal |
| 10 | GOLGA6L2 | Ssm | 40 | 105 | 38.1% | cbioportal |
| 12 | MST1P2 | Ssm | 36 | 105 | 34.3% | cbioportal |
| 13 | UBXN11 | Ssm | 34 | 105 | 32.4% | cbioportal |
| 14 | MUC3A | Ssm | 33 | 105 | 31.4% | cbioportal |
| 16 | MUC5B | Ssm | 32 | 105 | 30.5% | cbioportal |
| 15 | FRG2B | Ssm | 32 | 105 | 30.5% | cbioportal |
| 18 | TP53 | Ssm | 31 | 105 | 29.5% | cbioportal |
| 17 | BAGE2 | Ssm | 31 | 105 | 29.5% | cbioportal |
| 19 | HLA-DRB5 | Ssm | 30 | 105 | 28.6% | cbioportal |
| 20 | MAP3K1 | Ssm | 30 | 105 | 28.6% | cbioportal |
| 23 | HLA-DRB6 | Ssm | 29 | 105 | 27.6% | cbioportal |
| 24 | TRBV5-6 | Ssm | 29 | 105 | 27.6% | cbioportal |
| 21 | CNN2 | Ssm | 29 | 105 | 27.6% | cbioportal |
| 25 | URI1 | Ssm | 29 | 105 | 27.6% | cbioportal |
| 22 | DDX12P | Ssm | 29 | 105 | 27.6% | cbioportal |
| 30 | WNK1 | Ssm | 28 | 105 | 26.7% | cbioportal |
| 28 | KCNJ12 | Ssm | 28 | 105 | 26.7% | cbioportal |
| 27 | IGHV1-3 | Ssm | 28 | 105 | 26.7% | cbioportal |
| 26 | IGHJ6 | Ssm | 28 | 105 | 26.7% | cbioportal |
| 29 | LINC00955 | Ssm | 28 | 105 | 26.7% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07