Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
85 cases with simple somatic mutation data · 85 cases total · 2026-01-16 · mapped to Renal Pelvis and Ureter Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 41 |
| 85 |
| 48.2% |
| cbioportal |
| 2 | KMT2D | Ssm | 30 | 85 | 35.3% | cbioportal |
| 3 | KDM6A | Ssm | 29 | 85 | 34.1% | cbioportal |
| 4 | KMT2C | Ssm | 22 | 85 | 25.9% | cbioportal |
| 5 | STAG2 | Ssm | 19 | 85 | 22.4% | cbioportal |
| 7 | TP53 | Ssm | 15 | 85 | 17.6% | cbioportal |
| 6 | CREBBP | Ssm | 15 | 85 | 17.6% | cbioportal |
| 8 | TSC1 | Ssm | 14 | 85 | 16.5% | cbioportal |
| 9 | PIK3CA | Ssm | 13 | 85 | 15.3% | cbioportal |
| 10 | ARID1A | Ssm | 11 | 85 | 12.9% | cbioportal |
| 12 | TERT | Ssm | 10 | 85 | 11.8% | cbioportal |
| 11 | ATM | Ssm | 10 | 85 | 11.8% | cbioportal |
| 14 | SMARCA4 | Ssm | 9 | 85 | 10.6% | cbioportal |
| 13 | HRAS | Ssm | 9 | 85 | 10.6% | cbioportal |
| 15 | EP300 | Ssm | 8 | 85 | 9.4% | cbioportal |
| 16 | FAT1 | Ssm | 8 | 85 | 9.4% | cbioportal |
| 18 | EPHA5 | Ssm | 7 | 85 | 8.2% | cbioportal |
| 17 | ARID2 | Ssm | 7 | 85 | 8.2% | cbioportal |
| 21 | NF1 | Ssm | 6 | 85 | 7.1% | cbioportal |
| 19 | ERBB2 | Ssm | 6 | 85 | 7.1% | cbioportal |
| 22 | PBRM1 | Ssm | 6 | 85 | 7.1% | cbioportal |
| 20 | FBXW7 | Ssm | 6 | 85 | 7.1% | cbioportal |
| 33 | TET2 | Ssm | 5 | 85 | 5.9% | cbioportal |
| 26 | GRIN2A | Ssm | 5 | 85 | 5.9% | cbioportal |
| 28 | MET | Ssm | 5 | 85 | 5.9% | cbioportal |
| 27 | INPP4A | Ssm | 5 | 85 | 5.9% | cbioportal |
| 34 | TSC2 | Ssm | 5 | 85 | 5.9% | cbioportal |
| 24 | CDKN1A | Ssm | 5 | 85 | 5.9% | cbioportal |
| 25 | CDKN2A | Ssm | 5 | 85 | 5.9% | cbioportal |
| 32 | PTPRD | Ssm | 5 | 85 | 5.9% | cbioportal |
Data updated 21 days agoSource updated 2026-01-16