Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
69 cases with simple somatic mutation data · 69 cases total · 2026-03-09 · mapped to Endometrial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | ERBB2 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 69 |
| 69 |
| 100% |
| cbioportal |
| 2 | ARID1A | Ssm | 47 | 69 | 68.1% | cbioportal |
| 3 | PIK3CA | Ssm | 41 | 69 | 59.4% | cbioportal |
| 4 | PTEN | Ssm | 40 | 69 | 58% | cbioportal |
| 6 | TP53 | Ssm | 35 | 69 | 50.7% | cbioportal |
| 5 | KMT2D | Ssm | 35 | 69 | 50.7% | cbioportal |
| 7 | FBXW7 | Ssm | 27 | 69 | 39.1% | cbioportal |
| 15 | KMT2B | Ssm | 20 | 57 | 35.1% | cbioportal |
| 9 | NOTCH3 | Ssm | 24 | 69 | 34.8% | cbioportal |
| 8 | FAT1 | Ssm | 24 | 69 | 34.8% | cbioportal |
| 10 | ZFHX3 | Ssm | 23 | 68 | 33.8% | cbioportal |
| 104 | ARHGAP35 | Ssm | 8 | 25 | 32% | cbioportal |
| 11 | NOTCH1 | Ssm | 22 | 69 | 31.9% | cbioportal |
| 13 | KMT2C | Ssm | 21 | 69 | 30.4% | cbioportal |
| 12 | ERBB3 | Ssm | 21 | 69 | 30.4% | cbioportal |
| 14 | ATM | Ssm | 20 | 69 | 29% | cbioportal |
| 16 | POLE | Ssm | 20 | 69 | 29% | cbioportal |
| 17 | ARID1B | Ssm | 19 | 69 | 27.5% | cbioportal |
| 18 | CREBBP | Ssm | 19 | 69 | 27.5% | cbioportal |
| 19 | SMARCA4 | Ssm | 19 | 69 | 27.5% | cbioportal |
| 20 | ANKRD11 | Ssm | 18 | 68 | 26.5% | cbioportal |
| 33 | DROSHA | Ssm | 15 | 57 | 26.3% | cbioportal |
| 34 | INPPL1 | Ssm | 15 | 57 | 26.3% | cbioportal |
| 22 | MSH2 | Ssm | 18 | 69 | 26.1% | cbioportal |
| 21 | BCOR | Ssm | 18 | 69 | 26.1% | cbioportal |
| 24 | PIK3R1 | Ssm | 18 | 69 | 26.1% | cbioportal |
| 23 | NSD1 | Ssm | 18 | 69 | 26.1% | cbioportal |
| 26 | PPP2R1A | Ssm | 17 | 69 | 24.6% | cbioportal |
| 25 | CTCF | Ssm | 17 | 69 | 24.6% | cbioportal |
| 27 | SPEN | Ssm | 17 | 69 | 24.6% | cbioportal |
Data updated 21 days agoSource updated 2026-03-09