Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
2,621 cases with simple somatic mutation data · 2,621 cases total · 2026-01-08 · mapped to Lung Non-Small Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 1,123 |
| 2,621 |
| 42.8% |
| cbioportal |
| 2 | EGFR | Ssm | 662 | 2,621 | 25.3% | cbioportal |
| 3 | KRAS | Ssm | 523 | 2,621 | 20% | cbioportal |
| 4 | STK11 | Ssm | 222 | 2,621 | 8.5% | cbioportal |
| 11 | RBM10 | Ssm | 75 | 945 | 7.9% | cbioportal |
| 5 | KEAP1 | Ssm | 197 | 2,621 | 7.5% | cbioportal |
| 13 | PTPRD | Ssm | 70 | 945 | 7.4% | cbioportal |
| 10 | PTEN | Ssm | 77 | 1,257 | 6.1% | cbioportal |
| 12 | ATM | Ssm | 71 | 1,257 | 5.6% | cbioportal |
| 23 | ZFHX3 | Ssm | 52 | 940 | 5.5% | cbioportal |
| 14 | APC | Ssm | 69 | 1,257 | 5.5% | cbioportal |
| 15 | ARID1A | Ssm | 68 | 1,257 | 5.4% | cbioportal |
| 24 | FAT1 | Ssm | 51 | 954 | 5.3% | cbioportal |
| 16 | SMARCA4 | Ssm | 67 | 1,257 | 5.3% | cbioportal |
| 26 | PTPRT | Ssm | 50 | 945 | 5.3% | cbioportal |
| 25 | MGA | Ssm | 50 | 949 | 5.3% | cbioportal |
| 17 | NF1 | Ssm | 66 | 1,257 | 5.3% | cbioportal |
| 6 | MET | Ssm | 134 | 2,621 | 5.1% | cbioportal |
| 27 | KMT2D | Ssm | 48 | 954 | 5% | cbioportal |
| 19 | CDKN2A | Ssm | 63 | 1,257 | 5% | cbioportal |
| 20 | CTNNB1 | Ssm | 62 | 1,257 | 4.9% | cbioportal |
| 21 | RB1 | Ssm | 59 | 1,257 | 4.7% | cbioportal |
| 22 | SMAD4 | Ssm | 58 | 1,257 | 4.6% | cbioportal |
| 32 | GRIN2A | Ssm | 40 | 954 | 4.2% | cbioportal |
| 33 | KMT2C | Ssm | 38 | 954 | 4% | cbioportal |
| 7 | ERBB2 | Ssm | 103 | 2,621 | 3.9% | cbioportal |
| 35 | EPHA3 | Ssm | 37 | 954 | 3.9% | cbioportal |
| 8 | PIK3CA | Ssm | 101 | 2,621 | 3.9% | cbioportal |
| 39 | ARID1B | Ssm | 35 | 954 | 3.7% | cbioportal |
| 40 | ATR | Ssm | 35 | 954 | 3.7% | cbioportal |
Data updated 21 days agoSource updated 2026-01-08