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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
181 cases with simple somatic mutation data · 181 cases total · 2026-01-13 · mapped to Endometrial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | ARID1A |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 160 |
| 181 |
| 88.4% |
| cbioportal |
| 2 | PTEN | Ssm | 156 | 181 | 86.2% | cbioportal |
| 3 | KMT2D | Ssm | 122 | 181 | 67.4% | cbioportal |
| 5 | KMT2B | Ssm | 106 | 169 | 62.7% | cbioportal |
| 4 | PIK3CA | Ssm | 112 | 181 | 61.9% | cbioportal |
| 6 | CTCF | Ssm | 101 | 181 | 55.8% | cbioportal |
| 8 | INPPL1 | Ssm | 86 | 169 | 50.9% | cbioportal |
| 7 | ZFHX3 | Ssm | 90 | 180 | 50% | cbioportal |
| 9 | JAK1 | Ssm | 76 | 181 | 42% | cbioportal |
| 10 | RNF43 | Ssm | 76 | 181 | 42% | cbioportal |
| 11 | ARID1B | Ssm | 67 | 181 | 37% | cbioportal |
| 13 | PIK3R1 | Ssm | 62 | 181 | 34.3% | cbioportal |
| 12 | FAT1 | Ssm | 62 | 181 | 34.3% | cbioportal |
| 14 | CIC | Ssm | 54 | 181 | 29.8% | cbioportal |
| 15 | NOTCH3 | Ssm | 53 | 181 | 29.3% | cbioportal |
| 16 | ANKRD11 | Ssm | 51 | 180 | 28.3% | cbioportal |
| 18 | KMT2C | Ssm | 51 | 181 | 28.2% | cbioportal |
| 17 | BCOR | Ssm | 51 | 181 | 28.2% | cbioportal |
| 19 | CREBBP | Ssm | 50 | 181 | 27.6% | cbioportal |
| 21 | SMARCA4 | Ssm | 48 | 181 | 26.5% | cbioportal |
| 20 | MSH6 | Ssm | 48 | 181 | 26.5% | cbioportal |
| 23 | POLD1 | Ssm | 47 | 180 | 26.1% | cbioportal |
| 22 | KRAS | Ssm | 47 | 181 | 26% | cbioportal |
| 24 | FGFR2 | Ssm | 46 | 181 | 25.4% | cbioportal |
| 26 | SPEN | Ssm | 46 | 181 | 25.4% | cbioportal |
| 25 | PTPRS | Ssm | 46 | 181 | 25.4% | cbioportal |
| 27 | IRS2 | Ssm | 45 | 181 | 24.9% | cbioportal |
| 28 | FBXW7 | Ssm | 44 | 181 | 24.3% | cbioportal |
| 30 | CCND1 | Ssm | 43 | 181 | 23.8% | cbioportal |
| 29 | ATM | Ssm | 43 | 181 | 23.8% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13