Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
Loading cancer entity…
Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
151 cases with simple somatic mutation data · 151 cases total · 2026-01-08 · mapped to Myeloproliferative Neoplasm EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | JAK2 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 112 |
| 151 |
| 74.2% |
| cbioportal |
| 2 | CALR | Ssm | 25 | 151 | 16.6% | cbioportal |
| 3 | TET2 | Ssm | 21 | 151 | 13.9% | cbioportal |
| 4 | ASXL1 | Ssm | 12 | 151 | 7.9% | cbioportal |
| 5 | DNMT3A | Ssm | 12 | 151 | 7.9% | cbioportal |
| 6 | MPL | Ssm | 7 | 151 | 4.6% | cbioportal |
| 7 | EZH2 | Ssm | 4 | 151 | 2.6% | cbioportal |
| 8 | U2AF1 | Ssm | 4 | 151 | 2.6% | cbioportal |
| 15 | TP53 | Ssm | 3 | 151 | 2% | cbioportal |
| 12 | MUC16 | Ssm | 3 | 151 | 2% | cbioportal |
| 9 | CHEK2 | Ssm | 3 | 151 | 2% | cbioportal |
| 11 | KSR2 | Ssm | 3 | 151 | 2% | cbioportal |
| 13 | SF3B1 | Ssm | 3 | 151 | 2% | cbioportal |
| 10 | HUWE1 | Ssm | 3 | 151 | 2% | cbioportal |
| 14 | TG | Ssm | 3 | 151 | 2% | cbioportal |
| 30 | EPHA2 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 31 | EPHA7 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 32 | EZH1 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 33 | FARS2 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 34 | FAT2 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 35 | FAT4 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 36 | FBN2 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 37 | GABRB3 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 38 | GRIN2B | Ssm | 2 | 151 | 1.3% | cbioportal |
| 39 | HECW1 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 40 | HYDIN2 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 41 | IDH1 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 42 | IL6ST | Ssm | 2 | 151 | 1.3% | cbioportal |
| 43 | KANSL3 | Ssm | 2 | 151 | 1.3% | cbioportal |
| 44 | KIAA1217 | Ssm | 2 | 151 | 1.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-08