Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
444 cases with simple somatic mutation data · 444 cases total · 2026-01-16 · mapped to Prostate Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 163 |
| 444 |
| 36.7% |
| cbioportal |
| 2 | TTN | Ssm | 88 | 444 | 19.8% | cbioportal |
| 3 | MUC16 | Ssm | 67 | 444 | 15.1% | cbioportal |
| 4 | AR | Ssm | 61 | 444 | 13.7% | cbioportal |
| 5 | SYNE1 | Ssm | 49 | 444 | 11% | cbioportal |
| 6 | CSMD3 | Ssm | 43 | 444 | 9.7% | cbioportal |
| 7 | FOXA1 | Ssm | 41 | 444 | 9.2% | cbioportal |
| 8 | KMT2C | Ssm | 40 | 444 | 9% | cbioportal |
| 10 | KMT2D | Ssm | 37 | 444 | 8.3% | cbioportal |
| 9 | BRCA2 | Ssm | 37 | 444 | 8.3% | cbioportal |
| 11 | AHNAK2 | Ssm | 35 | 444 | 7.9% | cbioportal |
| 12 | HMCN1 | Ssm | 32 | 444 | 7.2% | cbioportal |
| 14 | USH2A | Ssm | 31 | 444 | 7% | cbioportal |
| 13 | APC | Ssm | 31 | 444 | 7% | cbioportal |
| 15 | CACNA1E | Ssm | 29 | 444 | 6.5% | cbioportal |
| 16 | OBSCN | Ssm | 29 | 444 | 6.5% | cbioportal |
| 20 | RYR1 | Ssm | 28 | 444 | 6.3% | cbioportal |
| 19 | PTEN | Ssm | 28 | 444 | 6.3% | cbioportal |
| 18 | PLEC | Ssm | 28 | 444 | 6.3% | cbioportal |
| 17 | LRP1B | Ssm | 28 | 444 | 6.3% | cbioportal |
| 22 | DCHS2 | Ssm | 27 | 444 | 6.1% | cbioportal |
| 21 | ATM | Ssm | 27 | 444 | 6.1% | cbioportal |
| 23 | FAT3 | Ssm | 27 | 444 | 6.1% | cbioportal |
| 25 | MUC4 | Ssm | 26 | 444 | 5.9% | cbioportal |
| 24 | CDK12 | Ssm | 26 | 444 | 5.9% | cbioportal |
| 26 | RYR3 | Ssm | 26 | 444 | 5.9% | cbioportal |
| 29 | RYR2 | Ssm | 25 | 444 | 5.6% | cbioportal |
| 28 | MACF1 | Ssm | 25 | 444 | 5.6% | cbioportal |
| 27 | ABCA13 | Ssm | 25 | 444 | 5.6% | cbioportal |
| 30 | SPOP | Ssm | 25 | 444 | 5.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-16