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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
44 cases with simple somatic mutation data · 44 cases total · 2026-01-13 · mapped to Endometrial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 22 |
| 44 |
| 50% |
| cbioportal |
| 2 | PIK3CA | Ssm | 21 | 44 | 47.7% | cbioportal |
| 3 | PTEN | Ssm | 21 | 44 | 47.7% | cbioportal |
| 4 | ARID1A | Ssm | 15 | 44 | 34.1% | cbioportal |
| 5 | FBXW7 | Ssm | 12 | 44 | 27.3% | cbioportal |
| 6 | KRAS | Ssm | 11 | 44 | 25% | cbioportal |
| 7 | PIK3R1 | Ssm | 9 | 44 | 20.5% | cbioportal |
| 8 | CTCF | Ssm | 8 | 44 | 18.2% | cbioportal |
| 9 | KMT2A | Ssm | 8 | 44 | 18.2% | cbioportal |
| 10 | KMT2B | Ssm | 8 | 44 | 18.2% | cbioportal |
| 11 | KMT2D | Ssm | 7 | 44 | 15.9% | cbioportal |
| 12 | JAK1 | Ssm | 6 | 44 | 13.6% | cbioportal |
| 14 | EP300 | Ssm | 5 | 44 | 11.4% | cbioportal |
| 15 | INPPL1 | Ssm | 5 | 44 | 11.4% | cbioportal |
| 16 | NFE2L2 | Ssm | 5 | 44 | 11.4% | cbioportal |
| 19 | ZFHX3 | Ssm | 5 | 44 | 11.4% | cbioportal |
| 18 | RNF43 | Ssm | 5 | 44 | 11.4% | cbioportal |
| 13 | BCOR | Ssm | 5 | 44 | 11.4% | cbioportal |
| 17 | POLD1 | Ssm | 5 | 44 | 11.4% | cbioportal |
| 21 | ATR | Ssm | 4 | 44 | 9.1% | cbioportal |
| 26 | PGR | Ssm | 4 | 44 | 9.1% | cbioportal |
| 24 | NOTCH4 | Ssm | 4 | 44 | 9.1% | cbioportal |
| 25 | PBRM1 | Ssm | 4 | 44 | 9.1% | cbioportal |
| 27 | PPP2R1A | Ssm | 4 | 44 | 9.1% | cbioportal |
| 20 | AR | Ssm | 4 | 44 | 9.1% | cbioportal |
| 22 | CREBBP | Ssm | 4 | 44 | 9.1% | cbioportal |
| 28 | RRAS2 | Ssm | 4 | 44 | 9.1% | cbioportal |
| 23 | ERF | Ssm | 4 | 44 | 9.1% | cbioportal |
| 41 | JAK3 | Ssm | 3 | 44 | 6.8% | cbioportal |
| 49 | RASA1 | Ssm | 3 | 44 | 6.8% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13