Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
199 cases with simple somatic mutation data · 219 cases total · 2026-04-07 · mapped to Intrahepatic Cholangiocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | IDH1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 45 |
| 199 |
| 22.6% |
| cbioportal |
| 2 | BAP1 | Ssm | 39 | 199 | 19.6% | cbioportal |
| 3 | ARID1A | Ssm | 35 | 199 | 17.6% | cbioportal |
| 4 | TP53 | Ssm | 32 | 199 | 16.1% | cbioportal |
| 5 | PBRM1 | Ssm | 25 | 199 | 12.6% | cbioportal |
| 6 | KRAS | Ssm | 19 | 199 | 9.5% | cbioportal |
| 7 | RASA1 | Ssm | 10 | 199 | 5% | cbioportal |
| 8 | BRAF | Ssm | 9 | 199 | 4.5% | cbioportal |
| 11 | PIK3CA | Ssm | 8 | 199 | 4% | cbioportal |
| 10 | IDH2 | Ssm | 8 | 199 | 4% | cbioportal |
| 9 | FGFR2 | Ssm | 8 | 199 | 4% | cbioportal |
| 12 | ARID2 | Ssm | 7 | 199 | 3.5% | cbioportal |
| 16 | PTPRT | Ssm | 7 | 199 | 3.5% | cbioportal |
| 13 | ATM | Ssm | 7 | 199 | 3.5% | cbioportal |
| 14 | CDKN2A | Ssm | 7 | 199 | 3.5% | cbioportal |
| 15 | NRAS | Ssm | 7 | 199 | 3.5% | cbioportal |
| 69 | TP53BP1 | Ssm | 3 | 89 | 3.4% | cbioportal |
| 68 | SOS1 | Ssm | 3 | 89 | 3.4% | cbioportal |
| 43 | ELF3 | Ssm | 3 | 89 | 3.4% | cbioportal |
| 61 | PREX2 | Ssm | 3 | 89 | 3.4% | cbioportal |
| 20 | TERT | Ssm | 6 | 199 | 3% | cbioportal |
| 17 | ATRX | Ssm | 6 | 199 | 3% | cbioportal |
| 19 | PTEN | Ssm | 6 | 199 | 3% | cbioportal |
| 18 | KMT2D | Ssm | 6 | 199 | 3% | cbioportal |
| 22 | RARA | Ssm | 5 | 199 | 2.5% | cbioportal |
| 24 | SMARCA4 | Ssm | 5 | 199 | 2.5% | cbioportal |
| 23 | RB1 | Ssm | 5 | 199 | 2.5% | cbioportal |
| 21 | DOT1L | Ssm | 5 | 199 | 2.5% | cbioportal |
| 37 | ZFHX3 | Ssm | 4 | 174 | 2.3% | cbioportal |
| 105 | MSH3 | Ssm | 2 | 89 | 2.2% | cbioportal |
Data updated 21 days agoSource updated 2026-04-07