Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
316 cases with simple somatic mutation data · 489 cases total · 2026-01-21 · mapped to High-Grade Serous Ovarian Cancer EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 303 |
| 316 |
| 95.9% |
| cbioportal |
| 2 | TTN | Ssm | 55 | 316 | 17.4% | cbioportal |
| 3 | BRCA1 | Ssm | 37 | 316 | 11.7% | cbioportal |
| 4 | BRCA2 | Ssm | 34 | 316 | 10.8% | cbioportal |
| 5 | USH2A | Ssm | 20 | 316 | 6.3% | cbioportal |
| 6 | CSMD3 | Ssm | 19 | 316 | 6% | cbioportal |
| 8 | MUC16 | Ssm | 18 | 316 | 5.7% | cbioportal |
| 7 | FAT3 | Ssm | 18 | 316 | 5.7% | cbioportal |
| 9 | LRP2 | Ssm | 15 | 316 | 4.7% | cbioportal |
| 10 | HMCN1 | Ssm | 14 | 316 | 4.4% | cbioportal |
| 11 | RYR2 | Ssm | 14 | 316 | 4.4% | cbioportal |
| 12 | LRP1B | Ssm | 13 | 316 | 4.1% | cbioportal |
| 15 | DNAH5 | Ssm | 12 | 316 | 3.8% | cbioportal |
| 14 | DNAH3 | Ssm | 12 | 316 | 3.8% | cbioportal |
| 16 | NF1 | Ssm | 12 | 316 | 3.8% | cbioportal |
| 13 | AHNAK | Ssm | 12 | 316 | 3.8% | cbioportal |
| 22 | TENM1 | Ssm | 11 | 316 | 3.5% | cbioportal |
| 17 | AHNAK2 | Ssm | 11 | 316 | 3.5% | cbioportal |
| 19 | FAT1 | Ssm | 11 | 316 | 3.5% | cbioportal |
| 20 | HYDIN | Ssm | 11 | 316 | 3.5% | cbioportal |
| 18 | APOB | Ssm | 11 | 316 | 3.5% | cbioportal |
| 21 | MUC17 | Ssm | 11 | 316 | 3.5% | cbioportal |
| 24 | HUWE1 | Ssm | 10 | 316 | 3.2% | cbioportal |
| 25 | LRRK2 | Ssm | 10 | 316 | 3.2% | cbioportal |
| 23 | COL6A3 | Ssm | 10 | 316 | 3.2% | cbioportal |
| 26 | RYR1 | Ssm | 10 | 316 | 3.2% | cbioportal |
| 40 | SYNE1 | Ssm | 9 | 316 | 2.8% | cbioportal |
| 39 | SI | Ssm | 9 | 316 | 2.8% | cbioportal |
| 38 | RNF213 | Ssm | 9 | 316 | 2.8% | cbioportal |
| 37 | PKHD1 | Ssm | 9 | 316 | 2.8% | cbioportal |
Data updated 21 days agoSource updated 2026-01-21