Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
90 cases with simple somatic mutation data · 90 cases total · 2026-06-23 · mapped to Lung Non-Small Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 26 |
| 90 |
| 28.9% |
| cbioportal |
| 2 | ALK | Ssm | 18 | 90 | 20% | cbioportal |
| 5 | USP8 | Ssm | 9 | 46 | 19.6% | cbioportal |
| 3 | CDKN2A | Ssm | 11 | 90 | 12.2% | cbioportal |
| 4 | KMT2C | Ssm | 10 | 90 | 11.1% | cbioportal |
| 26 | HLA-C | Ssm | 5 | 46 | 10.9% | cbioportal |
| 58 | MARCHF7 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 62 | MTTP | Ssm | 4 | 37 | 10.8% | cbioportal |
| 75 | ZNF141 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 6 | ZFHX3 | Ssm | 9 | 86 | 10.5% | cbioportal |
| 7 | SETD2 | Ssm | 8 | 90 | 8.9% | cbioportal |
| 69 | REST | Ssm | 4 | 46 | 8.7% | cbioportal |
| 13 | MST1 | Ssm | 7 | 86 | 8.1% | cbioportal |
| 125 | PPIAL4G | Ssm | 3 | 37 | 8.1% | cbioportal |
| 89 | CWC22 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 100 | HLA-G | Ssm | 3 | 37 | 8.1% | cbioportal |
| 130 | SLFN13 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 91 | DPP6 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 119 | NPAP1 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 9 | ATM | Ssm | 7 | 90 | 7.8% | cbioportal |
| 12 | FAT1 | Ssm | 7 | 90 | 7.8% | cbioportal |
| 11 | ERBB2 | Ssm | 7 | 90 | 7.8% | cbioportal |
| 8 | ARID1A | Ssm | 7 | 90 | 7.8% | cbioportal |
| 16 | TSC2 | Ssm | 7 | 90 | 7.8% | cbioportal |
| 10 | BRCA1 | Ssm | 7 | 90 | 7.8% | cbioportal |
| 14 | PIK3C2G | Ssm | 7 | 90 | 7.8% | cbioportal |
| 15 | PTPRD | Ssm | 7 | 90 | 7.8% | cbioportal |
| 21 | SOS1 | Ssm | 6 | 80 | 7.5% | cbioportal |
| 20 | POLE | Ssm | 6 | 90 | 6.7% | cbioportal |
| 19 | PMS2 | Ssm | 6 | 90 | 6.7% | cbioportal |
Data updated 21 days agoSource updated 2026-06-23