Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
73 cases with simple somatic mutation data · 73 cases total · 2026-01-16 · mapped to Diffuse Glioma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | IDH1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 68 |
| 73 |
| 93.2% |
| cbioportal |
| 2 | TERT | Ssm | 45 | 73 | 61.6% | cbioportal |
| 3 | CIC | Ssm | 31 | 73 | 42.5% | cbioportal |
| 4 | TP53 | Ssm | 31 | 73 | 42.5% | cbioportal |
| 5 | ATRX | Ssm | 25 | 73 | 34.2% | cbioportal |
| 6 | NOTCH1 | Ssm | 12 | 73 | 16.4% | cbioportal |
| 7 | FUBP1 | Ssm | 11 | 73 | 15.1% | cbioportal |
| 8 | ARID1B | Ssm | 8 | 73 | 11% | cbioportal |
| 11 | PIK3CA | Ssm | 7 | 73 | 9.6% | cbioportal |
| 12 | SMARCA4 | Ssm | 7 | 73 | 9.6% | cbioportal |
| 10 | KMT2D | Ssm | 7 | 73 | 9.6% | cbioportal |
| 9 | KMT2C | Ssm | 7 | 73 | 9.6% | cbioportal |
| 13 | FAT1 | Ssm | 6 | 73 | 8.2% | cbioportal |
| 47 | PRKD1 | Ssm | 3 | 40 | 7.5% | cbioportal |
| 38 | KMT2B | Ssm | 3 | 40 | 7.5% | cbioportal |
| 15 | ASXL1 | Ssm | 5 | 73 | 6.8% | cbioportal |
| 17 | PDGFRB | Ssm | 5 | 73 | 6.8% | cbioportal |
| 14 | ARID1A | Ssm | 5 | 73 | 6.8% | cbioportal |
| 16 | IDH2 | Ssm | 5 | 73 | 6.8% | cbioportal |
| 24 | SETD2 | Ssm | 4 | 73 | 5.5% | cbioportal |
| 23 | NF1 | Ssm | 4 | 73 | 5.5% | cbioportal |
| 19 | CREBBP | Ssm | 4 | 73 | 5.5% | cbioportal |
| 18 | BRCA1 | Ssm | 4 | 73 | 5.5% | cbioportal |
| 22 | MDC1 | Ssm | 4 | 73 | 5.5% | cbioportal |
| 20 | DIS3 | Ssm | 4 | 73 | 5.5% | cbioportal |
| 21 | DOT1L | Ssm | 4 | 73 | 5.5% | cbioportal |
| 111 | TP53BP1 | Ssm | 2 | 40 | 5% | cbioportal |
| 86 | MAPKAP1 | Ssm | 2 | 40 | 5% | cbioportal |
| 83 | KMT5A | Ssm | 2 | 40 | 5% | cbioportal |
| 106 | RTEL1 | Ssm | 2 | 40 | 5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-16