Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
136 cases with simple somatic mutation data · 136 cases total · 2026-01-08 · mapped to Myeloid Neoplasm EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 32 |
| 136 |
| 23.5% |
| cbioportal |
| 2 | ASXL1 | Ssm | 21 | 136 | 15.4% | cbioportal |
| 3 | SRSF2 | Ssm | 19 | 136 | 14% | cbioportal |
| 6 | RUNX1 | Ssm | 9 | 71 | 12.7% | cbioportal |
| 4 | IDH2 | Ssm | 16 | 136 | 11.8% | cbioportal |
| 9 | TET2 | Ssm | 7 | 71 | 9.9% | cbioportal |
| 5 | DNMT3A | Ssm | 11 | 136 | 8.1% | cbioportal |
| 10 | NRAS | Ssm | 5 | 71 | 7% | cbioportal |
| 7 | SF3B1 | Ssm | 9 | 136 | 6.6% | cbioportal |
| 8 | IDH1 | Ssm | 8 | 136 | 5.9% | cbioportal |
| 12 | GATA2 | Ssm | 4 | 71 | 5.6% | cbioportal |
| 14 | PHF6 | Ssm | 4 | 71 | 5.6% | cbioportal |
| 15 | WT1 | Ssm | 4 | 71 | 5.6% | cbioportal |
| 13 | NPM1 | Ssm | 4 | 71 | 5.6% | cbioportal |
| 19 | STAG2 | Ssm | 3 | 71 | 4.2% | cbioportal |
| 17 | FCGBP | Ssm | 3 | 71 | 4.2% | cbioportal |
| 16 | BCOR | Ssm | 3 | 71 | 4.2% | cbioportal |
| 18 | KIT | Ssm | 3 | 71 | 4.2% | cbioportal |
| 11 | U2AF1 | Ssm | 5 | 136 | 3.7% | cbioportal |
| 20 | ADAMTS17 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 24 | DMBT1 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 29 | KLHL1 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 32 | NHS | Ssm | 2 | 60 | 3.3% | cbioportal |
| 23 | DENND3 | Ssm | 2 | 60 | 3.3% | cbioportal |
| 37 | SMC1A | Ssm | 2 | 71 | 2.8% | cbioportal |
| 34 | RUNX1T1 | Ssm | 2 | 71 | 2.8% | cbioportal |
| 21 | CBL | Ssm | 2 | 71 | 2.8% | cbioportal |
| 33 | PTPRT | Ssm | 2 | 71 | 2.8% | cbioportal |
| 25 | ETV6 | Ssm | 2 | 71 | 2.8% | cbioportal |
| 27 | FLT3 | Ssm | 2 | 71 | 2.8% | cbioportal |
Data updated 21 days agoSource updated 2026-01-08