Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
279 cases with simple somatic mutation data · 279 cases total · 2026-01-07 · mapped to Head and Neck Squamous Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 207 |
| 279 |
| 74.2% |
| cbioportal |
| 2 | TTN | Ssm | 127 | 279 | 45.5% | cbioportal |
| 3 | CSMD3 | Ssm | 66 | 279 | 23.7% | cbioportal |
| 4 | FAT1 | Ssm | 64 | 279 | 22.9% | cbioportal |
| 5 | CDKN2A | Ssm | 63 | 279 | 22.6% | cbioportal |
| 6 | MUC16 | Ssm | 60 | 279 | 21.5% | cbioportal |
| 7 | PIK3CA | Ssm | 58 | 279 | 20.8% | cbioportal |
| 8 | LRP1B | Ssm | 57 | 279 | 20.4% | cbioportal |
| 9 | NOTCH1 | Ssm | 52 | 279 | 18.6% | cbioportal |
| 10 | KMT2D | Ssm | 49 | 279 | 17.6% | cbioportal |
| 11 | SYNE1 | Ssm | 49 | 279 | 17.6% | cbioportal |
| 12 | FLG | Ssm | 44 | 279 | 15.8% | cbioportal |
| 13 | DNAH5 | Ssm | 42 | 279 | 15.1% | cbioportal |
| 14 | PCLO | Ssm | 42 | 279 | 15.1% | cbioportal |
| 15 | USH2A | Ssm | 36 | 279 | 12.9% | cbioportal |
| 16 | PKHD1L1 | Ssm | 35 | 279 | 12.5% | cbioportal |
| 17 | SI | Ssm | 32 | 279 | 11.5% | cbioportal |
| 20 | RYR2 | Ssm | 31 | 279 | 11.1% | cbioportal |
| 19 | FRG1BP | Ssm | 31 | 279 | 11.1% | cbioportal |
| 18 | DMD | Ssm | 31 | 279 | 11.1% | cbioportal |
| 21 | FAM135B | Ssm | 30 | 279 | 10.8% | cbioportal |
| 22 | NSD1 | Ssm | 29 | 279 | 10.4% | cbioportal |
| 23 | RELN | Ssm | 28 | 279 | 10% | cbioportal |
| 24 | COL11A1 | Ssm | 27 | 279 | 9.7% | cbioportal |
| 25 | LAMA2 | Ssm | 27 | 279 | 9.7% | cbioportal |
| 26 | CUBN | Ssm | 26 | 279 | 9.3% | cbioportal |
| 27 | DNAH7 | Ssm | 26 | 279 | 9.3% | cbioportal |
| 29 | CSMD1 | Ssm | 25 | 279 | 9% | cbioportal |
| 30 | MUC17 | Ssm | 25 | 279 | 9% | cbioportal |
| 32 | PAPPA2 | Ssm | 25 | 279 | 9% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07