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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
23 cases with simple somatic mutation data · 24 cases total · 2026-01-20 · mapped to Endometrial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | PTEN | Ssm | 15 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 24 |
| 62.5% |
| cbioportal |
| 2 | ARID1A | Ssm | 14 | 24 | 58.3% | cbioportal |
| 3 | PIK3CA | Ssm | 12 | 24 | 50% | cbioportal |
| 4 | PIK3R1 | Ssm | 10 | 24 | 41.7% | cbioportal |
| 5 | CTNNB1 | Ssm | 9 | 24 | 37.5% | cbioportal |
| 6 | KRAS | Ssm | 6 | 24 | 25% | cbioportal |
| 7 | BCOR | Ssm | 5 | 24 | 20.8% | cbioportal |
| 8 | FGFR2 | Ssm | 4 | 24 | 16.7% | cbioportal |
| 9 | KMT2D | Ssm | 4 | 24 | 16.7% | cbioportal |
| 11 | ZFHX3 | Ssm | 4 | 24 | 16.7% | cbioportal |
| 10 | PIK3CG | Ssm | 4 | 24 | 16.7% | cbioportal |
| 15 | KMT2B | Ssm | 3 | 23 | 13% | cbioportal |
| 14 | JAK1 | Ssm | 3 | 24 | 12.5% | cbioportal |
| 13 | CTCF | Ssm | 3 | 24 | 12.5% | cbioportal |
| 18 | SPOP | Ssm | 3 | 24 | 12.5% | cbioportal |
| 19 | TP53 | Ssm | 3 | 24 | 12.5% | cbioportal |
| 12 | CCND1 | Ssm | 3 | 24 | 12.5% | cbioportal |
| 17 | NOTCH1 | Ssm | 3 | 24 | 12.5% | cbioportal |
| 16 | MAP3K1 | Ssm | 3 | 24 | 12.5% | cbioportal |
| 108 | REST | Ssm | 1 | 9 | 11.1% | cbioportal |
| 68 | ETAA1 | Ssm | 1 | 9 | 11.1% | cbioportal |
| 78 | GAB1 | Ssm | 1 | 9 | 11.1% | cbioportal |
| 124 | SPRTN | Ssm | 1 | 9 | 11.1% | cbioportal |
| 120 | SMARCE1 | Ssm | 1 | 9 | 11.1% | cbioportal |
| 27 | INPPL1 | Ssm | 2 | 23 | 8.7% | cbioportal |
| 39 | SLX4 | Ssm | 2 | 23 | 8.7% | cbioportal |
| 38 | RASA1 | Ssm | 2 | 24 | 8.3% | cbioportal |
| 20 | ACVR1 | Ssm | 2 | 24 | 8.3% | cbioportal |
| 21 | AKT1 | Ssm | 2 | 24 | 8.3% | cbioportal |
| 22 | ANKRD11 | Ssm | 2 | 24 | 8.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-20