Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
1,270 cases with simple somatic mutation data · 1,270 cases total · 2026-01-20 · mapped to Histiocytic and Dendritic Cell Neoplasm EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | BRAF |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 224 |
| 1,270 |
| 17.6% |
| cbioportal |
| 2 | MAP2K1 | Ssm | 113 | 1,270 | 8.9% | cbioportal |
| 3 | DNMT3A | Ssm | 104 | 1,270 | 8.2% | cbioportal |
| 4 | KRAS | Ssm | 102 | 1,270 | 8% | cbioportal |
| 5 | TET2 | Ssm | 66 | 1,270 | 5.2% | cbioportal |
| 6 | NRAS | Ssm | 33 | 1,270 | 2.6% | cbioportal |
| 7 | TP53 | Ssm | 28 | 1,270 | 2.2% | cbioportal |
| 9 | NF1 | Ssm | 25 | 1,270 | 2% | cbioportal |
| 8 | ATM | Ssm | 25 | 1,270 | 2% | cbioportal |
| 10 | ASXL1 | Ssm | 24 | 1,270 | 1.9% | cbioportal |
| 11 | CBL | Ssm | 17 | 1,270 | 1.3% | cbioportal |
| 12 | GNAS | Ssm | 13 | 1,270 | 1% | cbioportal |
| 13 | ARAF | Ssm | 11 | 1,270 | 0.9% | cbioportal |
| 14 | CSF1R | Ssm | 10 | 1,270 | 0.8% | cbioportal |
| 15 | NOTCH1 | Ssm | 10 | 1,270 | 0.8% | cbioportal |
| 19 | NOTCH2 | Ssm | 8 | 1,270 | 0.6% | cbioportal |
| 20 | PTPN11 | Ssm | 8 | 1,270 | 0.6% | cbioportal |
| 16 | BCOR | Ssm | 8 | 1,270 | 0.6% | cbioportal |
| 18 | JAK2 | Ssm | 8 | 1,270 | 0.6% | cbioportal |
| 21 | SF3B1 | Ssm | 8 | 1,270 | 0.6% | cbioportal |
| 17 | CREBBP | Ssm | 8 | 1,270 | 0.6% | cbioportal |
| 22 | ARID1A | Ssm | 7 | 1,270 | 0.6% | cbioportal |
| 25 | NOTCH3 | Ssm | 7 | 1,270 | 0.6% | cbioportal |
| 23 | FOXO1 | Ssm | 7 | 1,270 | 0.6% | cbioportal |
| 24 | KMT2D | Ssm | 7 | 1,270 | 0.6% | cbioportal |
| 26 | BRCA1 | Ssm | 6 | 1,270 | 0.5% | cbioportal |
| 27 | CARD11 | Ssm | 6 | 1,270 | 0.5% | cbioportal |
| 28 | STAG2 | Ssm | 6 | 1,270 | 0.5% | cbioportal |
| 33 | RAF1 | Ssm | 5 | 1,270 | 0.4% | cbioportal |
| 30 | H1-4 | Ssm | 5 | 1,270 | 0.4% | cbioportal |
Data updated 21 days agoSource updated 2026-01-20