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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
279 cases with simple somatic mutation data · 292 cases total · 2026-01-13 · mapped to Papillary Renal Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 40 |
| 279 |
| 14.3% |
| cbioportal |
| 2 | MUC16 | Ssm | 22 | 279 | 7.9% | cbioportal |
| 3 | MET | Ssm | 20 | 279 | 7.2% | cbioportal |
| 4 | KMT2C | Ssm | 18 | 279 | 6.5% | cbioportal |
| 7 | SETD2 | Ssm | 15 | 279 | 5.4% | cbioportal |
| 6 | PKHD1 | Ssm | 15 | 279 | 5.4% | cbioportal |
| 5 | BLTP1 | Ssm | 15 | 279 | 5.4% | cbioportal |
| 9 | CUBN | Ssm | 14 | 279 | 5% | cbioportal |
| 8 | BAP1 | Ssm | 14 | 279 | 5% | cbioportal |
| 10 | FAT1 | Ssm | 14 | 279 | 5% | cbioportal |
| 11 | KMT2D | Ssm | 13 | 279 | 4.7% | cbioportal |
| 13 | USH2A | Ssm | 13 | 279 | 4.7% | cbioportal |
| 12 | SYNE1 | Ssm | 13 | 279 | 4.7% | cbioportal |
| 14 | DNAH8 | Ssm | 12 | 279 | 4.3% | cbioportal |
| 15 | HERC2 | Ssm | 12 | 279 | 4.3% | cbioportal |
| 16 | SYNE2 | Ssm | 12 | 279 | 4.3% | cbioportal |
| 17 | WDFY3 | Ssm | 12 | 279 | 4.3% | cbioportal |
| 18 | ARID1A | Ssm | 11 | 279 | 3.9% | cbioportal |
| 20 | OBSCN | Ssm | 11 | 279 | 3.9% | cbioportal |
| 21 | PBRM1 | Ssm | 11 | 279 | 3.9% | cbioportal |
| 22 | PCF11 | Ssm | 11 | 279 | 3.9% | cbioportal |
| 19 | LRP2 | Ssm | 11 | 279 | 3.9% | cbioportal |
| 25 | MACF1 | Ssm | 10 | 279 | 3.6% | cbioportal |
| 26 | SRRM2 | Ssm | 10 | 279 | 3.6% | cbioportal |
| 23 | CUL3 | Ssm | 10 | 279 | 3.6% | cbioportal |
| 24 | KDM6A | Ssm | 10 | 279 | 3.6% | cbioportal |
| 32 | PCLO | Ssm | 9 | 279 | 3.2% | cbioportal |
| 30 | HERC1 | Ssm | 9 | 279 | 3.2% | cbioportal |
| 29 | BIRC6 | Ssm | 9 | 279 | 3.2% | cbioportal |
| 28 | ANK3 | Ssm | 9 | 279 | 3.2% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13