Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
37 cases with simple somatic mutation data · 47 cases total · 2026-01-19 · mapped to Renal Pelvis and Ureter Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 | KMT2D | Ssm | 13 | 37 | 35.1% | cbioportal |
| 2 | TP53 | Ssm | 12 | 37 | 32.4% | cbioportal |
| 3 | FGFR3 | Ssm | 11 | 37 | 29.7% | cbioportal |
| 4 | PIK3CA | Ssm | 8 | 37 | 21.6% | cbioportal |
| 5 | ATM | Ssm | 7 | 37 | 18.9% | cbioportal |
| 7 | CDKN1A | Ssm | 5 | 37 | 13.5% | cbioportal |
| 6 | ADGRV1 | Ssm | 5 | 37 | 13.5% | cbioportal |
| 9 | OBSCN | Ssm | 5 | 37 | 13.5% | cbioportal |
| 8 | EYS | Ssm | 5 | 37 | 13.5% | cbioportal |
| 19 | UTRN | Ssm | 4 | 37 | 10.8% | cbioportal |
| 20 | ZFHX4 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 11 | ARID1A | Ssm | 4 | 37 | 10.8% | cbioportal |
| 16 | RNF213 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 10 | AFF1 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 12 | KDM6A | Ssm | 4 | 37 | 10.8% | cbioportal |
| 13 | MACF1 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 17 | SPTAN1 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 14 | MUC17 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 15 | PLXNA2 | Ssm | 4 | 37 | 10.8% | cbioportal |
| 18 | TTN | Ssm | 4 | 37 | 10.8% | cbioportal |
| 41 | DOCK10 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 42 | DOCK7 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 43 | DYNC2H1 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 44 | EARS2 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 45 | EPRS1 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 46 | ERBB3 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 47 | ERF | Ssm | 3 | 37 | 8.1% | cbioportal |
| 48 | FAT4 | Ssm | 3 | 37 | 8.1% | cbioportal |
| 49 | FLNC | Ssm | 3 | 37 | 8.1% | cbioportal |
| 50 | HCFC1 | Ssm | 3 | 37 | 8.1% | cbioportal |
Data updated 21 days agoSource updated 2026-01-19