Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
91 cases with simple somatic mutation data · 91 cases total · 2026-01-07 · mapped to Diffuse Glioma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TERT | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 56 |
| 91 |
| 61.5% |
| cbioportal |
| 2 | TP53 | Ssm | 54 | 91 | 59.3% | cbioportal |
| 3 | IDH1 | Ssm | 25 | 91 | 27.5% | cbioportal |
| 4 | ATRX | Ssm | 23 | 91 | 25.3% | cbioportal |
| 5 | PTEN | Ssm | 19 | 91 | 20.9% | cbioportal |
| 6 | PIK3CA | Ssm | 17 | 91 | 18.7% | cbioportal |
| 7 | EGFR | Ssm | 16 | 91 | 17.6% | cbioportal |
| 8 | ARID2 | Ssm | 15 | 91 | 16.5% | cbioportal |
| 9 | ARID1A | Ssm | 13 | 91 | 14.3% | cbioportal |
| 10 | NF1 | Ssm | 13 | 91 | 14.3% | cbioportal |
| 11 | ZFHX3 | Ssm | 13 | 91 | 14.3% | cbioportal |
| 12 | CIC | Ssm | 12 | 91 | 13.2% | cbioportal |
| 15 | NOTCH3 | Ssm | 10 | 91 | 11% | cbioportal |
| 16 | RB1 | Ssm | 10 | 91 | 11% | cbioportal |
| 13 | CREBBP | Ssm | 10 | 91 | 11% | cbioportal |
| 14 | FAT1 | Ssm | 10 | 91 | 11% | cbioportal |
| 17 | PDGFRA | Ssm | 9 | 91 | 9.9% | cbioportal |
| 22 | SMARCA4 | Ssm | 8 | 91 | 8.8% | cbioportal |
| 20 | PIK3R2 | Ssm | 8 | 91 | 8.8% | cbioportal |
| 21 | POLE | Ssm | 8 | 91 | 8.8% | cbioportal |
| 19 | MTOR | Ssm | 8 | 91 | 8.8% | cbioportal |
| 18 | KMT2C | Ssm | 8 | 91 | 8.8% | cbioportal |
| 33 | PTPRS | Ssm | 7 | 91 | 7.7% | cbioportal |
| 32 | PARP1 | Ssm | 7 | 91 | 7.7% | cbioportal |
| 31 | PAK5 | Ssm | 7 | 91 | 7.7% | cbioportal |
| 35 | TSC2 | Ssm | 7 | 91 | 7.7% | cbioportal |
| 30 | NCOR1 | Ssm | 7 | 91 | 7.7% | cbioportal |
| 29 | NCOA3 | Ssm | 7 | 91 | 7.7% | cbioportal |
| 23 | AR | Ssm | 7 | 91 | 7.7% | cbioportal |
| 25 | KMT2D | Ssm | 7 | 91 | 7.7% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07