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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
110 cases with simple somatic mutation data · 110 cases total · 2026-01-14 · mapped to Lung Squamous Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 101 |
| 110 |
| 91.8% |
| cbioportal |
| 2 | TTN | Ssm | 72 | 110 | 65.5% | cbioportal |
| 3 | CSMD3 | Ssm | 42 | 110 | 38.2% | cbioportal |
| 4 | USH2A | Ssm | 42 | 110 | 38.2% | cbioportal |
| 5 | RYR2 | Ssm | 39 | 110 | 35.5% | cbioportal |
| 6 | ZFHX4 | Ssm | 34 | 110 | 30.9% | cbioportal |
| 7 | MUC16 | Ssm | 33 | 110 | 30% | cbioportal |
| 8 | SYNE1 | Ssm | 32 | 110 | 29.1% | cbioportal |
| 9 | LRP1B | Ssm | 31 | 110 | 28.2% | cbioportal |
| 10 | FAM135B | Ssm | 28 | 110 | 25.5% | cbioportal |
| 11 | KMT2D | Ssm | 26 | 110 | 23.6% | cbioportal |
| 12 | DNAH5 | Ssm | 24 | 110 | 21.8% | cbioportal |
| 13 | FSIP2 | Ssm | 24 | 110 | 21.8% | cbioportal |
| 14 | COL22A1 | Ssm | 22 | 110 | 20% | cbioportal |
| 15 | COL11A1 | Ssm | 21 | 110 | 19.1% | cbioportal |
| 16 | PCLO | Ssm | 21 | 110 | 19.1% | cbioportal |
| 18 | MUC19 | Ssm | 20 | 110 | 18.2% | cbioportal |
| 17 | LRTM3 | Ssm | 20 | 110 | 18.2% | cbioportal |
| 21 | EYS | Ssm | 19 | 110 | 17.3% | cbioportal |
| 25 | XIRP2 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 23 | PRDM9 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 20 | CTNND2 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 24 | RYR3 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 19 | CDH10 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 22 | PCDH15 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 29 | NAV3 | Ssm | 18 | 110 | 16.4% | cbioportal |
| 26 | ADAMTS12 | Ssm | 18 | 110 | 16.4% | cbioportal |
| 28 | CUBN | Ssm | 18 | 110 | 16.4% | cbioportal |
| 31 | ZNF804B | Ssm | 18 | 110 | 16.4% | cbioportal |
| 30 | PKHD1L1 | Ssm | 18 | 110 | 16.4% | cbioportal |
Data updated 21 days agoSource updated 2026-01-14