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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
63 cases with simple somatic mutation data · 68 cases total · 2026-01-07 · mapped to Gastroesophageal Junction Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 45 |
| 63 |
| 71.4% |
| cbioportal |
| 3 | TTN | Ssm | 11 | 31 | 35.5% | cbioportal |
| 7 | SYNE1 | Ssm | 7 | 31 | 22.6% | cbioportal |
| 5 | LRP1B | Ssm | 7 | 31 | 22.6% | cbioportal |
| 6 | PCLO | Ssm | 7 | 31 | 22.6% | cbioportal |
| 10 | CSMD2 | Ssm | 6 | 31 | 19.4% | cbioportal |
| 11 | OBSCN | Ssm | 6 | 31 | 19.4% | cbioportal |
| 2 | CDKN2A | Ssm | 11 | 63 | 17.5% | cbioportal |
| 19 | MXRA5 | Ssm | 5 | 31 | 16.1% | cbioportal |
| 16 | DNAH8 | Ssm | 5 | 31 | 16.1% | cbioportal |
| 14 | CSMD3 | Ssm | 5 | 31 | 16.1% | cbioportal |
| 23 | UNC13C | Ssm | 5 | 31 | 16.1% | cbioportal |
| 13 | COL4A4 | Ssm | 5 | 31 | 16.1% | cbioportal |
| 15 | CUBN | Ssm | 5 | 31 | 16.1% | cbioportal |
| 21 | TENM4 | Ssm | 5 | 31 | 16.1% | cbioportal |
| 18 | MUC16 | Ssm | 5 | 31 | 16.1% | cbioportal |
| 4 | PTPRT | Ssm | 10 | 63 | 15.9% | cbioportal |
| 32 | CSMD1 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 30 | CNTN6 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 31 | CNTNAP4 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 55 | TTC6 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 54 | SLC12A1 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 52 | RIMS2 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 51 | RIMS1 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 47 | PLEC | Ssm | 4 | 31 | 12.9% | cbioportal |
| 46 | PIEZO1 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 45 | PABPC3 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 44 | NRXN1 | Ssm | 4 | 31 | 12.9% | cbioportal |
| 43 | NRK | Ssm | 4 | 31 | 12.9% | cbioportal |
| 41 | MAGEC1 | Ssm | 4 | 31 | 12.9% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07