Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
179 cases with simple somatic mutation data · 184 cases total · 2026-06-04 · mapped to Pancreatic Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 | KRAS | Ssm | 117 | 179 | 65.4% | cbioportal |
| 2 | TP53 | Ssm | 107 | 179 | 59.8% | cbioportal |
| 3 | SMAD4 | Ssm | 37 | 179 | 20.7% | cbioportal |
| 4 | CDKN2A | Ssm | 35 | 179 | 19.6% | cbioportal |
| 5 | TTN | Ssm | 29 | 179 | 16.2% | cbioportal |
| 6 | MUC16 | Ssm | 13 | 179 | 7.3% | cbioportal |
| 7 | RNF43 | Ssm | 11 | 179 | 6.1% | cbioportal |
| 8 | CSMD2 | Ssm | 10 | 179 | 5.6% | cbioportal |
| 9 | RYR1 | Ssm | 10 | 179 | 5.6% | cbioportal |
| 11 | PCDH15 | Ssm | 9 | 179 | 5% | cbioportal |
| 10 | ARID1A | Ssm | 9 | 179 | 5% | cbioportal |
| 17 | OBSCN | Ssm | 8 | 179 | 4.5% | cbioportal |
| 16 | MYO18B | Ssm | 8 | 179 | 4.5% | cbioportal |
| 14 | FLG | Ssm | 8 | 179 | 4.5% | cbioportal |
| 13 | CACNA1B | Ssm | 8 | 179 | 4.5% | cbioportal |
| 19 | TGFBR2 | Ssm | 8 | 179 | 4.5% | cbioportal |
| 15 | HECW2 | Ssm | 8 | 179 | 4.5% | cbioportal |
| 18 | RNF213 | Ssm | 8 | 179 | 4.5% | cbioportal |
| 12 | ATM | Ssm | 8 | 179 | 4.5% | cbioportal |
| 39 | USH2A | Ssm | 7 | 179 | 3.9% | cbioportal |
| 31 | KMT2C | Ssm | 7 | 179 | 3.9% | cbioportal |
| 30 | KDM6A | Ssm | 7 | 179 | 3.9% | cbioportal |
| 29 | GNAS | Ssm | 7 | 179 | 3.9% | cbioportal |
| 28 | GLI3 | Ssm | 7 | 179 | 3.9% | cbioportal |
| 27 | FLNC | Ssm | 7 | 179 | 3.9% | cbioportal |
| 26 | FAT3 | Ssm | 7 | 179 | 3.9% | cbioportal |
| 25 | FAT2 | Ssm | 7 | 179 | 3.9% | cbioportal |
| 24 | DSCAML1 | Ssm | 7 | 179 | 3.9% | cbioportal |
| 38 | SCN5A | Ssm | 7 | 179 | 3.9% | cbioportal |
| 20 | ADAMTS12 | Ssm | 7 | 179 | 3.9% | cbioportal |
Data updated 21 days agoSource updated 2026-06-04