Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
74 cases with simple somatic mutation data · 74 cases total · 2026-01-07 · mapped to Head and Neck Squamous Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 46 |
| 74 |
| 62.2% |
| cbioportal |
| 2 | TTN | Ssm | 22 | 74 | 29.7% | cbioportal |
| 3 | SYNE1 | Ssm | 15 | 74 | 20.3% | cbioportal |
| 4 | MUC16 | Ssm | 14 | 74 | 18.9% | cbioportal |
| 5 | CSMD3 | Ssm | 12 | 74 | 16.2% | cbioportal |
| 6 | USH2A | Ssm | 11 | 74 | 14.9% | cbioportal |
| 7 | RYR2 | Ssm | 10 | 74 | 13.5% | cbioportal |
| 12 | FAT3 | Ssm | 9 | 74 | 12.2% | cbioportal |
| 15 | PRDM9 | Ssm | 9 | 74 | 12.2% | cbioportal |
| 9 | COL22A1 | Ssm | 9 | 74 | 12.2% | cbioportal |
| 16 | ZFHX4 | Ssm | 9 | 74 | 12.2% | cbioportal |
| 13 | LRP1B | Ssm | 9 | 74 | 12.2% | cbioportal |
| 8 | CDKN2A | Ssm | 9 | 74 | 12.2% | cbioportal |
| 14 | NOTCH1 | Ssm | 9 | 74 | 12.2% | cbioportal |
| 11 | FAT1 | Ssm | 9 | 74 | 12.2% | cbioportal |
| 10 | CUBN | Ssm | 9 | 74 | 12.2% | cbioportal |
| 17 | FAT2 | Ssm | 8 | 74 | 10.8% | cbioportal |
| 19 | HMCN1 | Ssm | 8 | 74 | 10.8% | cbioportal |
| 21 | NAV3 | Ssm | 8 | 74 | 10.8% | cbioportal |
| 18 | FAT4 | Ssm | 8 | 74 | 10.8% | cbioportal |
| 20 | KMT2D | Ssm | 8 | 74 | 10.8% | cbioportal |
| 22 | PCLO | Ssm | 8 | 74 | 10.8% | cbioportal |
| 24 | FREM2 | Ssm | 7 | 74 | 9.5% | cbioportal |
| 28 | THSD7A | Ssm | 7 | 74 | 9.5% | cbioportal |
| 27 | SI | Ssm | 7 | 74 | 9.5% | cbioportal |
| 26 | RIMS2 | Ssm | 7 | 74 | 9.5% | cbioportal |
| 29 | ZNF804B | Ssm | 7 | 74 | 9.5% | cbioportal |
| 25 | NSD1 | Ssm | 7 | 74 | 9.5% | cbioportal |
| 23 | FLG | Ssm | 7 | 74 | 9.5% | cbioportal |
| 44 | PAPPA2 | Ssm | 6 | 74 | 8.1% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07