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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
96 cases with simple somatic mutation data · 96 cases total · 2026-01-12 · mapped to Pancreatic Neuroendocrine Tumor EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| MEN1 |
| Ssm |
| 50 |
| 96 |
| 52.1% |
| cbioportal |
| 2 | DAXX | Ssm | 41 | 96 | 42.7% | cbioportal |
| 3 | ATRX | Ssm | 21 | 96 | 21.9% | cbioportal |
| 4 | TSC2 | Ssm | 18 | 96 | 18.8% | cbioportal |
| 5 | SETD2 | Ssm | 17 | 96 | 17.7% | cbioportal |
| 6 | TP53 | Ssm | 12 | 96 | 12.5% | cbioportal |
| 8 | PTEN | Ssm | 11 | 96 | 11.5% | cbioportal |
| 7 | ARID1A | Ssm | 11 | 96 | 11.5% | cbioportal |
| 9 | BRAF | Ssm | 10 | 96 | 10.4% | cbioportal |
| 118 | PTP4A1 | Ssm | 2 | 21 | 9.5% | cbioportal |
| 10 | KMT2C | Ssm | 7 | 96 | 7.3% | cbioportal |
| 11 | NOTCH3 | Ssm | 7 | 96 | 7.3% | cbioportal |
| 16 | TERT | Ssm | 6 | 96 | 6.3% | cbioportal |
| 12 | ATM | Ssm | 6 | 96 | 6.3% | cbioportal |
| 15 | NOTCH1 | Ssm | 6 | 96 | 6.3% | cbioportal |
| 13 | KMT2D | Ssm | 6 | 96 | 6.3% | cbioportal |
| 14 | MED12 | Ssm | 6 | 96 | 6.3% | cbioportal |
| 17 | ARID2 | Ssm | 5 | 96 | 5.2% | cbioportal |
| 18 | BRCA2 | Ssm | 5 | 96 | 5.2% | cbioportal |
| 19 | CREBBP | Ssm | 5 | 96 | 5.2% | cbioportal |
| 20 | FAT1 | Ssm | 5 | 96 | 5.2% | cbioportal |
| 194 | LYN | Ssm | 1 | 21 | 4.8% | cbioportal |
| 193 | KMT2B | Ssm | 1 | 21 | 4.8% | cbioportal |
| 22 | ERBB4 | Ssm | 4 | 96 | 4.2% | cbioportal |
| 26 | LATS2 | Ssm | 4 | 96 | 4.2% | cbioportal |
| 25 | KRAS | Ssm | 4 | 96 | 4.2% | cbioportal |
| 30 | VHL | Ssm | 4 | 96 | 4.2% | cbioportal |
| 24 | KMT2A | Ssm | 4 | 96 | 4.2% | cbioportal |
| 28 | SMAD4 | Ssm | 4 | 96 | 4.2% | cbioportal |
| 23 | IGF1R | Ssm | 4 | 96 | 4.2% | cbioportal |
Data updated 21 days agoSource updated 2026-01-12