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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
123 cases with simple somatic mutation data · 251 cases total · 2026-01-14 · mapped to Acute Leukemia of Ambiguous Lineage EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | WT1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 20 |
| 123 |
| 16.3% |
| cbioportal |
| 2 | NRAS | Ssm | 14 | 123 | 11.4% | cbioportal |
| 3 | RUNX1 | Ssm | 10 | 123 | 8.1% | cbioportal |
| 5 | PTPN11 | Ssm | 8 | 123 | 6.5% | cbioportal |
| 4 | KMT2D | Ssm | 8 | 123 | 6.5% | cbioportal |
| 7 | JAK3 | Ssm | 7 | 123 | 5.7% | cbioportal |
| 6 | FLT3 | Ssm | 7 | 123 | 5.7% | cbioportal |
| 12 | SETD2 | Ssm | 6 | 123 | 4.9% | cbioportal |
| 11 | NOTCH1 | Ssm | 6 | 123 | 4.9% | cbioportal |
| 9 | LRP1 | Ssm | 6 | 123 | 4.9% | cbioportal |
| 8 | CREBBP | Ssm | 6 | 123 | 4.9% | cbioportal |
| 10 | MUC4 | Ssm | 6 | 123 | 4.9% | cbioportal |
| 15 | HMCN2 | Ssm | 5 | 123 | 4.1% | cbioportal |
| 18 | USP9X | Ssm | 5 | 123 | 4.1% | cbioportal |
| 16 | TNRC18 | Ssm | 5 | 123 | 4.1% | cbioportal |
| 19 | VSTM2A | Ssm | 5 | 123 | 4.1% | cbioportal |
| 17 | TTN | Ssm | 5 | 123 | 4.1% | cbioportal |
| 13 | ASXL1 | Ssm | 5 | 123 | 4.1% | cbioportal |
| 14 | DDX3X | Ssm | 5 | 123 | 4.1% | cbioportal |
| 24 | GALNT9 | Ssm | 4 | 123 | 3.3% | cbioportal |
| 33 | PLAAT1 | Ssm | 4 | 123 | 3.3% | cbioportal |
| 31 | NSD2 | Ssm | 4 | 123 | 3.3% | cbioportal |
| 22 | FAM186A | Ssm | 4 | 123 | 3.3% | cbioportal |
| 32 | NTN1 | Ssm | 4 | 123 | 3.3% | cbioportal |
| 34 | TNIP3 | Ssm | 4 | 123 | 3.3% | cbioportal |
| 25 | HDX | Ssm | 4 | 123 | 3.3% | cbioportal |
| 26 | HEATR5B | Ssm | 4 | 123 | 3.3% | cbioportal |
| 28 | LONRF3 | Ssm | 4 | 123 | 3.3% | cbioportal |
| 20 | CNTNAP2 | Ssm | 4 | 123 | 3.3% | cbioportal |
| 27 | HYDIN | Ssm | 4 | 123 | 3.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-14