Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
1,417 cases with simple somatic mutation data · 1,417 cases total · 2026-01-16 · mapped to Prostate Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 411 |
| 1,417 |
| 29% |
| cbioportal |
| 2 | SPOP | Ssm | 200 | 1,417 | 14.1% | cbioportal |
| 3 | FOXA1 | Ssm | 197 | 1,417 | 13.9% | cbioportal |
| 4 | APC | Ssm | 124 | 1,417 | 8.8% | cbioportal |
| 5 | PTEN | Ssm | 119 | 1,417 | 8.4% | cbioportal |
| 6 | KMT2C | Ssm | 81 | 1,417 | 5.7% | cbioportal |
| 8 | ZFHX3 | Ssm | 75 | 1,361 | 5.5% | cbioportal |
| 7 | KMT2D | Ssm | 76 | 1,417 | 5.4% | cbioportal |
| 9 | CDK12 | Ssm | 67 | 1,417 | 4.7% | cbioportal |
| 10 | CTNNB1 | Ssm | 61 | 1,417 | 4.3% | cbioportal |
| 11 | PIK3CA | Ssm | 60 | 1,417 | 4.2% | cbioportal |
| 12 | ATM | Ssm | 59 | 1,417 | 4.2% | cbioportal |
| 13 | BRCA2 | Ssm | 56 | 1,417 | 4% | cbioportal |
| 14 | AR | Ssm | 53 | 1,417 | 3.7% | cbioportal |
| 15 | PIK3R1 | Ssm | 48 | 1,417 | 3.4% | cbioportal |
| 16 | KDM6A | Ssm | 44 | 1,417 | 3.1% | cbioportal |
| 17 | MGA | Ssm | 39 | 1,361 | 2.9% | cbioportal |
| 18 | RB1 | Ssm | 36 | 1,417 | 2.5% | cbioportal |
| 19 | MED12 | Ssm | 35 | 1,417 | 2.5% | cbioportal |
| 20 | PTPRD | Ssm | 31 | 1,417 | 2.2% | cbioportal |
| 21 | GRIN2A | Ssm | 28 | 1,417 | 2% | cbioportal |
| 22 | ASXL2 | Ssm | 27 | 1,417 | 1.9% | cbioportal |
| 25 | SPEN | Ssm | 26 | 1,417 | 1.8% | cbioportal |
| 23 | EPHB1 | Ssm | 26 | 1,417 | 1.8% | cbioportal |
| 24 | JAK1 | Ssm | 26 | 1,417 | 1.8% | cbioportal |
| 26 | NCOR1 | Ssm | 25 | 1,417 | 1.8% | cbioportal |
| 27 | SF3B1 | Ssm | 25 | 1,417 | 1.8% | cbioportal |
| 28 | ARID1A | Ssm | 23 | 1,417 | 1.6% | cbioportal |
| 29 | ASXL1 | Ssm | 22 | 1,417 | 1.6% | cbioportal |
| 32 | KMT2A | Ssm | 22 | 1,417 | 1.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-16