Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
186 cases with simple somatic mutation data · 186 cases total · 2026-04-07 · mapped to Lung Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | EGFR | Ssm | 183 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 186 |
| 98.4% |
| cbioportal |
| 2 | TP53 | Ssm | 128 | 186 | 68.8% | cbioportal |
| 3 | PIK3CA | Ssm | 20 | 186 | 10.8% | cbioportal |
| 4 | RB1 | Ssm | 19 | 186 | 10.2% | cbioportal |
| 5 | CTNNB1 | Ssm | 18 | 186 | 9.7% | cbioportal |
| 6 | RBM10 | Ssm | 14 | 186 | 7.5% | cbioportal |
| 7 | PTEN | Ssm | 13 | 186 | 7% | cbioportal |
| 8 | ARID1A | Ssm | 10 | 186 | 5.4% | cbioportal |
| 10 | PTPRD | Ssm | 9 | 186 | 4.8% | cbioportal |
| 9 | ATR | Ssm | 9 | 186 | 4.8% | cbioportal |
| 13 | ZFHX3 | Ssm | 8 | 185 | 4.3% | cbioportal |
| 11 | APC | Ssm | 8 | 186 | 4.3% | cbioportal |
| 12 | KMT2C | Ssm | 8 | 186 | 4.3% | cbioportal |
| 14 | SMARCA4 | Ssm | 7 | 186 | 3.8% | cbioportal |
| 17 | NOTCH4 | Ssm | 6 | 186 | 3.2% | cbioportal |
| 18 | TSC2 | Ssm | 6 | 186 | 3.2% | cbioportal |
| 15 | ASXL1 | Ssm | 6 | 186 | 3.2% | cbioportal |
| 16 | FAT1 | Ssm | 6 | 186 | 3.2% | cbioportal |
| 27 | PLCG2 | Ssm | 5 | 185 | 2.7% | cbioportal |
| 23 | MGA | Ssm | 5 | 185 | 2.7% | cbioportal |
| 21 | KEAP1 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 26 | NOTCH2 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 20 | H1-2 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 19 | EPHA5 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 25 | NBN | Ssm | 5 | 186 | 2.7% | cbioportal |
| 24 | MTOR | Ssm | 5 | 186 | 2.7% | cbioportal |
| 22 | MED12 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 29 | TET1 | Ssm | 5 | 186 | 2.7% | cbioportal |
| 28 | PTPRT | Ssm | 5 | 186 | 2.7% | cbioportal |
| 35 | CSF3R | Ssm | 4 | 185 | 2.2% | cbioportal |
Data updated 21 days agoSource updated 2026-04-07