Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
110 cases with simple somatic mutation data · 110 cases total · 2026-01-16 · mapped to Lung Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 59 |
| 110 |
| 53.6% |
| cbioportal |
| 2 | EGFR | Ssm | 38 | 110 | 34.5% | cbioportal |
| 3 | MUC16 | Ssm | 37 | 110 | 33.6% | cbioportal |
| 4 | RYR2 | Ssm | 35 | 110 | 31.8% | cbioportal |
| 5 | TTN | Ssm | 35 | 110 | 31.8% | cbioportal |
| 6 | LRP1B | Ssm | 34 | 110 | 30.9% | cbioportal |
| 7 | CSMD3 | Ssm | 33 | 110 | 30% | cbioportal |
| 8 | KRAS | Ssm | 33 | 110 | 30% | cbioportal |
| 9 | USH2A | Ssm | 28 | 110 | 25.5% | cbioportal |
| 10 | ZFHX4 | Ssm | 26 | 110 | 23.6% | cbioportal |
| 11 | FAT3 | Ssm | 23 | 110 | 20.9% | cbioportal |
| 12 | COL11A1 | Ssm | 22 | 110 | 20% | cbioportal |
| 14 | SPTA1 | Ssm | 21 | 110 | 19.1% | cbioportal |
| 13 | FAM135B | Ssm | 21 | 110 | 19.1% | cbioportal |
| 15 | CSMD1 | Ssm | 20 | 110 | 18.2% | cbioportal |
| 17 | STK11 | Ssm | 20 | 110 | 18.2% | cbioportal |
| 16 | PCLO | Ssm | 20 | 110 | 18.2% | cbioportal |
| 18 | APOB | Ssm | 19 | 110 | 17.3% | cbioportal |
| 21 | NRXN1 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 19 | EYS | Ssm | 19 | 110 | 17.3% | cbioportal |
| 22 | PCDH15 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 20 | MUC17 | Ssm | 19 | 110 | 17.3% | cbioportal |
| 23 | CNTNAP2 | Ssm | 18 | 110 | 16.4% | cbioportal |
| 24 | FLG | Ssm | 18 | 110 | 16.4% | cbioportal |
| 25 | XIRP2 | Ssm | 18 | 110 | 16.4% | cbioportal |
| 30 | NAV3 | Ssm | 17 | 110 | 15.5% | cbioportal |
| 27 | ANK2 | Ssm | 17 | 110 | 15.5% | cbioportal |
| 26 | ADAMTS12 | Ssm | 17 | 110 | 15.5% | cbioportal |
| 29 | LRTM3 | Ssm | 17 | 110 | 15.5% | cbioportal |
| 31 | RIMS2 | Ssm | 17 | 110 | 15.5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-16