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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
192 cases with simple somatic mutation data · 192 cases total · 2026-01-05 · mapped to Bladder Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 108 |
| 192 |
| 56.3% |
| cbioportal |
| 2 | KMT2D | Ssm | 62 | 192 | 32.3% | cbioportal |
| 3 | ARID1A | Ssm | 55 | 192 | 28.6% | cbioportal |
| 4 | RNF213 | Ssm | 54 | 192 | 28.1% | cbioportal |
| 5 | KDM6A | Ssm | 48 | 192 | 25% | cbioportal |
| 6 | LRP1B | Ssm | 47 | 192 | 24.5% | cbioportal |
| 7 | AKAP9 | Ssm | 39 | 192 | 20.3% | cbioportal |
| 8 | SPEN | Ssm | 38 | 192 | 19.8% | cbioportal |
| 9 | BRCA2 | Ssm | 37 | 192 | 19.3% | cbioportal |
| 10 | KMT2C | Ssm | 35 | 192 | 18.2% | cbioportal |
| 11 | EP300 | Ssm | 34 | 192 | 17.7% | cbioportal |
| 12 | FGFR3 | Ssm | 34 | 192 | 17.7% | cbioportal |
| 13 | RB1 | Ssm | 32 | 192 | 16.7% | cbioportal |
| 14 | ATM | Ssm | 31 | 192 | 16.1% | cbioportal |
| 15 | PRKDC | Ssm | 31 | 192 | 16.1% | cbioportal |
| 16 | KMT2A | Ssm | 30 | 192 | 15.6% | cbioportal |
| 19 | PIK3CA | Ssm | 29 | 192 | 15.1% | cbioportal |
| 17 | CREBBP | Ssm | 29 | 192 | 15.1% | cbioportal |
| 18 | PDE4DIP | Ssm | 29 | 192 | 15.1% | cbioportal |
| 21 | PCM1 | Ssm | 26 | 192 | 13.5% | cbioportal |
| 20 | KIAA1549 | Ssm | 26 | 192 | 13.5% | cbioportal |
| 24 | MYH9 | Ssm | 25 | 192 | 13% | cbioportal |
| 23 | KNL1 | Ssm | 25 | 192 | 13% | cbioportal |
| 26 | RECQL4 | Ssm | 25 | 192 | 13% | cbioportal |
| 22 | FANCA | Ssm | 25 | 192 | 13% | cbioportal |
| 25 | NOTCH1 | Ssm | 25 | 192 | 13% | cbioportal |
| 27 | ERBB3 | Ssm | 24 | 192 | 12.5% | cbioportal |
| 28 | ERCC2 | Ssm | 23 | 192 | 12% | cbioportal |
| 29 | CNTRL | Ssm | 22 | 192 | 11.5% | cbioportal |
| 30 | TRIP11 | Ssm | 22 | 192 | 11.5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-05