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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
120 cases with simple somatic mutation data · 120 cases total · 2026-01-13 · mapped to Lung Small Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 103 |
| 120 |
| 85.8% |
| cbioportal |
| 2 | RB1 | Ssm | 87 | 120 | 72.5% | cbioportal |
| 3 | TTN | Ssm | 77 | 120 | 64.2% | cbioportal |
| 4 | RYR2 | Ssm | 54 | 120 | 45% | cbioportal |
| 5 | LRP1B | Ssm | 51 | 120 | 42.5% | cbioportal |
| 6 | MUC16 | Ssm | 49 | 120 | 40.8% | cbioportal |
| 7 | ZFHX4 | Ssm | 46 | 120 | 38.3% | cbioportal |
| 8 | USH2A | Ssm | 44 | 120 | 36.7% | cbioportal |
| 9 | CSMD3 | Ssm | 42 | 120 | 35% | cbioportal |
| 10 | NAV3 | Ssm | 35 | 120 | 29.2% | cbioportal |
| 11 | PCDH15 | Ssm | 32 | 120 | 26.7% | cbioportal |
| 12 | COL11A1 | Ssm | 31 | 120 | 25.8% | cbioportal |
| 13 | CSMD1 | Ssm | 28 | 120 | 23.3% | cbioportal |
| 14 | EYS | Ssm | 27 | 120 | 22.5% | cbioportal |
| 16 | SYNE1 | Ssm | 27 | 120 | 22.5% | cbioportal |
| 15 | MUC17 | Ssm | 27 | 120 | 22.5% | cbioportal |
| 18 | FAM135B | Ssm | 26 | 120 | 21.7% | cbioportal |
| 17 | ANKRD30B | Ssm | 26 | 120 | 21.7% | cbioportal |
| 20 | TMEM132D | Ssm | 25 | 120 | 20.8% | cbioportal |
| 19 | FSIP2 | Ssm | 25 | 120 | 20.8% | cbioportal |
| 21 | ERICH3 | Ssm | 24 | 120 | 20% | cbioportal |
| 22 | PKHD1 | Ssm | 24 | 120 | 20% | cbioportal |
| 23 | SI | Ssm | 24 | 120 | 20% | cbioportal |
| 25 | RYR1 | Ssm | 23 | 120 | 19.2% | cbioportal |
| 24 | PKHD1L1 | Ssm | 23 | 120 | 19.2% | cbioportal |
| 27 | TENM1 | Ssm | 23 | 120 | 19.2% | cbioportal |
| 28 | XIRP2 | Ssm | 23 | 120 | 19.2% | cbioportal |
| 26 | SPTA1 | Ssm | 23 | 120 | 19.2% | cbioportal |
| 32 | NCAM2 | Ssm | 22 | 120 | 18.3% | cbioportal |
| 34 | TNR | Ssm | 22 | 120 | 18.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13