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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
48 cases with simple somatic mutation data · 48 cases total · 2026-01-20 · mapped to Rectal Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 36 |
| 48 |
| 75% |
| cbioportal |
| 5 | TTN | Ssm | 9 | 17 | 52.9% | cbioportal |
| 2 | APC | Ssm | 23 | 48 | 47.9% | cbioportal |
| 3 | KRAS | Ssm | 17 | 48 | 35.4% | cbioportal |
| 12 | SPTBN4 | Ssm | 6 | 17 | 35.3% | cbioportal |
| 9 | BSN | Ssm | 6 | 17 | 35.3% | cbioportal |
| 13 | SYNE1 | Ssm | 6 | 17 | 35.3% | cbioportal |
| 15 | DNAH11 | Ssm | 5 | 17 | 29.4% | cbioportal |
| 16 | MAST4 | Ssm | 5 | 17 | 29.4% | cbioportal |
| 4 | SMAD4 | Ssm | 12 | 48 | 25% | cbioportal |
| 19 | ARHGAP24 | Ssm | 4 | 17 | 23.5% | cbioportal |
| 18 | ACTA1 | Ssm | 4 | 17 | 23.5% | cbioportal |
| 33 | TBL3 | Ssm | 4 | 17 | 23.5% | cbioportal |
| 30 | PAPLN | Ssm | 4 | 17 | 23.5% | cbioportal |
| 23 | FLG | Ssm | 4 | 17 | 23.5% | cbioportal |
| 93 | TRPC3 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 44 | CLTCL1 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 49 | DMD | Ssm | 3 | 17 | 17.6% | cbioportal |
| 92 | TLN1 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 50 | DNAH9 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 94 | TSKS | Ssm | 3 | 17 | 17.6% | cbioportal |
| 51 | DOCK10 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 52 | DSCAM | Ssm | 3 | 17 | 17.6% | cbioportal |
| 86 | SERPINB2 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 85 | SAMD9L | Ssm | 3 | 17 | 17.6% | cbioportal |
| 54 | FCRL6 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 55 | FGD3 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 84 | RIN1 | Ssm | 3 | 17 | 17.6% | cbioportal |
| 69 | NEB | Ssm | 3 | 17 | 17.6% | cbioportal |
| 37 | ALS2CL | Ssm | 3 | 17 | 17.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-20