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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
29 cases with simple somatic mutation data · 29 cases total · 2026-01-13 · mapped to Lung Small Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 26 |
| 29 |
| 89.7% |
| cbioportal |
| 2 | RB1 | Ssm | 19 | 29 | 65.5% | cbioportal |
| 4 | USH2A | Ssm | 13 | 29 | 44.8% | cbioportal |
| 3 | LRP1B | Ssm | 13 | 29 | 44.8% | cbioportal |
| 5 | TTN | Ssm | 11 | 29 | 37.9% | cbioportal |
| 6 | CSMD3 | Ssm | 10 | 29 | 34.5% | cbioportal |
| 7 | PKHD1 | Ssm | 10 | 29 | 34.5% | cbioportal |
| 9 | MUC17 | Ssm | 9 | 29 | 31% | cbioportal |
| 10 | PRDM9 | Ssm | 9 | 29 | 31% | cbioportal |
| 8 | COL11A1 | Ssm | 9 | 29 | 31% | cbioportal |
| 13 | SYNE1 | Ssm | 8 | 29 | 27.6% | cbioportal |
| 15 | ZNF536 | Ssm | 8 | 29 | 27.6% | cbioportal |
| 14 | ZNF521 | Ssm | 8 | 29 | 27.6% | cbioportal |
| 11 | DMD | Ssm | 8 | 29 | 27.6% | cbioportal |
| 12 | SPHKAP | Ssm | 8 | 29 | 27.6% | cbioportal |
| 22 | ZNF804A | Ssm | 7 | 29 | 24.1% | cbioportal |
| 20 | TMEM132D | Ssm | 7 | 29 | 24.1% | cbioportal |
| 19 | TKTL2 | Ssm | 7 | 29 | 24.1% | cbioportal |
| 16 | CSMD2 | Ssm | 7 | 29 | 24.1% | cbioportal |
| 21 | TNN | Ssm | 7 | 29 | 24.1% | cbioportal |
| 17 | FLG | Ssm | 7 | 29 | 24.1% | cbioportal |
| 18 | SI | Ssm | 7 | 29 | 24.1% | cbioportal |
| 25 | COL22A1 | Ssm | 6 | 29 | 20.7% | cbioportal |
| 31 | HERC2 | Ssm | 6 | 29 | 20.7% | cbioportal |
| 26 | DNAH9 | Ssm | 6 | 29 | 20.7% | cbioportal |
| 27 | ERBB4 | Ssm | 6 | 29 | 20.7% | cbioportal |
| 37 | TNR | Ssm | 6 | 29 | 20.7% | cbioportal |
| 29 | FAT4 | Ssm | 6 | 29 | 20.7% | cbioportal |
| 36 | TFAP2D | Ssm | 6 | 29 | 20.7% | cbioportal |
| 33 | NCAM2 | Ssm | 6 | 29 | 20.7% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13