Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
469 cases with simple somatic mutation data · 469 cases total · 2026-01-07 · mapped to Gastrointestinal Stromal Tumor EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KIT |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 353 |
| 469 |
| 75.3% |
| cbioportal |
| 2 | PDGFRA | Ssm | 52 | 469 | 11.1% | cbioportal |
| 3 | NF1 | Ssm | 21 | 469 | 4.5% | cbioportal |
| 4 | TP53 | Ssm | 21 | 469 | 4.5% | cbioportal |
| 5 | SETD2 | Ssm | 19 | 469 | 4.1% | cbioportal |
| 7 | MGA | Ssm | 18 | 447 | 4% | cbioportal |
| 6 | MAX | Ssm | 18 | 469 | 3.8% | cbioportal |
| 8 | RB1 | Ssm | 17 | 469 | 3.6% | cbioportal |
| 49 | APLNR | Ssm | 2 | 61 | 3.3% | cbioportal |
| 9 | CSDE1 | Ssm | 11 | 342 | 3.2% | cbioportal |
| 10 | PTEN | Ssm | 10 | 469 | 2.1% | cbioportal |
| 12 | SDHA | Ssm | 9 | 469 | 1.9% | cbioportal |
| 11 | PIK3CA | Ssm | 9 | 469 | 1.9% | cbioportal |
| 14 | TSC1 | Ssm | 8 | 469 | 1.7% | cbioportal |
| 13 | ARID1A | Ssm | 8 | 469 | 1.7% | cbioportal |
| 175 | REST | Ssm | 1 | 61 | 1.6% | cbioportal |
| 113 | CYP19A1 | Ssm | 1 | 61 | 1.6% | cbioportal |
| 138 | KBTBD4 | Ssm | 1 | 61 | 1.6% | cbioportal |
| 15 | CREBBP | Ssm | 7 | 469 | 1.5% | cbioportal |
| 16 | KMT2D | Ssm | 7 | 469 | 1.5% | cbioportal |
| 18 | ROS1 | Ssm | 6 | 469 | 1.3% | cbioportal |
| 17 | MTOR | Ssm | 6 | 469 | 1.3% | cbioportal |
| 23 | ZFHX3 | Ssm | 5 | 447 | 1.1% | cbioportal |
| 19 | ATM | Ssm | 5 | 469 | 1.1% | cbioportal |
| 21 | KMT2A | Ssm | 5 | 469 | 1.1% | cbioportal |
| 22 | KMT2C | Ssm | 5 | 469 | 1.1% | cbioportal |
| 20 | CBL | Ssm | 5 | 469 | 1.1% | cbioportal |
| 38 | KMT2B | Ssm | 3 | 342 | 0.9% | cbioportal |
| 27 | IRS2 | Ssm | 4 | 469 | 0.9% | cbioportal |
| 31 | TET2 | Ssm | 4 | 469 | 0.9% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07