Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
1,882 cases with simple somatic mutation data · 1,882 cases total · 2026-01-13 · mapped to Endometrial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | PTEN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 941 |
| 1,882 |
| 50% |
| cbioportal |
| 2 | TP53 | Ssm | 850 | 1,882 | 45.2% | cbioportal |
| 3 | PIK3CA | Ssm | 824 | 1,882 | 43.8% | cbioportal |
| 4 | ARID1A | Ssm | 793 | 1,882 | 42.1% | cbioportal |
| 5 | PIK3R1 | Ssm | 484 | 1,882 | 25.7% | cbioportal |
| 6 | KRAS | Ssm | 357 | 1,882 | 19% | cbioportal |
| 7 | CTCF | Ssm | 305 | 1,882 | 16.2% | cbioportal |
| 8 | CTNNB1 | Ssm | 296 | 1,882 | 15.7% | cbioportal |
| 9 | FBXW7 | Ssm | 276 | 1,882 | 14.7% | cbioportal |
| 10 | ZFHX3 | Ssm | 237 | 1,824 | 13% | cbioportal |
| 13 | KMT2B | Ssm | 208 | 1,661 | 12.5% | cbioportal |
| 11 | KMT2D | Ssm | 231 | 1,882 | 12.3% | cbioportal |
| 12 | PPP2R1A | Ssm | 226 | 1,882 | 12% | cbioportal |
| 15 | INPPL1 | Ssm | 171 | 1,661 | 10.3% | cbioportal |
| 14 | BCOR | Ssm | 184 | 1,882 | 9.8% | cbioportal |
| 16 | JAK1 | Ssm | 171 | 1,882 | 9.1% | cbioportal |
| 17 | RNF43 | Ssm | 154 | 1,882 | 8.2% | cbioportal |
| 18 | FGFR2 | Ssm | 151 | 1,882 | 8% | cbioportal |
| 19 | ATM | Ssm | 139 | 1,882 | 7.4% | cbioportal |
| 20 | NF1 | Ssm | 118 | 1,882 | 6.3% | cbioportal |
| 21 | NSD1 | Ssm | 103 | 1,882 | 5.5% | cbioportal |
| 22 | ARID1B | Ssm | 102 | 1,882 | 5.4% | cbioportal |
| 24 | KMT2C | Ssm | 96 | 1,882 | 5.1% | cbioportal |
| 23 | ARID5B | Ssm | 96 | 1,882 | 5.1% | cbioportal |
| 25 | SOX17 | Ssm | 93 | 1,882 | 4.9% | cbioportal |
| 26 | CCND1 | Ssm | 92 | 1,882 | 4.9% | cbioportal |
| 28 | POLE | Ssm | 91 | 1,882 | 4.8% | cbioportal |
| 27 | FAT1 | Ssm | 91 | 1,882 | 4.8% | cbioportal |
| 29 | MED12 | Ssm | 89 | 1,882 | 4.7% | cbioportal |
| 30 | RASA1 | Ssm | 88 | 1,882 | 4.7% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13