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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
32 cases with simple somatic mutation data · 42 cases total · 2026-01-07 · mapped to Diffuse Glioma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | PTEN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 6 |
| 32 |
| 18.8% |
| cbioportal |
| 3 | RYR2 | Ssm | 4 | 32 | 12.5% | cbioportal |
| 2 | IDH1 | Ssm | 4 | 32 | 12.5% | cbioportal |
| 6 | MUC16 | Ssm | 3 | 32 | 9.4% | cbioportal |
| 9 | TP53 | Ssm | 3 | 32 | 9.4% | cbioportal |
| 8 | PIK3CA | Ssm | 3 | 32 | 9.4% | cbioportal |
| 5 | FAM83H | Ssm | 3 | 32 | 9.4% | cbioportal |
| 4 | DSG3 | Ssm | 3 | 32 | 9.4% | cbioportal |
| 7 | NF1 | Ssm | 3 | 32 | 9.4% | cbioportal |
| 19 | FAT2 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 20 | FGL2 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 21 | FILIP1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 22 | FUBP1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 23 | HYDIN | Ssm | 2 | 32 | 6.3% | cbioportal |
| 24 | LAMA3 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 25 | LRP2 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 26 | LRTM3 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 27 | MAN2B2 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 28 | MTOR | Ssm | 2 | 32 | 6.3% | cbioportal |
| 29 | MYH1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 30 | N4BP2 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 31 | NCAM1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 32 | OR4K5 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 33 | PHF12 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 34 | PKHD1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 35 | RYR1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 36 | SCNN1G | Ssm | 2 | 32 | 6.3% | cbioportal |
| 37 | STEAP3 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 38 | SVEP1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 39 | TUBA3C | Ssm | 2 | 32 | 6.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07