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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
295 cases with simple somatic mutation data · 295 cases total · 2026-01-13 · mapped to Gastric Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 166 |
| 295 |
| 56.3% |
| cbioportal |
| 2 | TP53 | Ssm | 138 | 295 | 46.8% | cbioportal |
| 3 | MUC16 | Ssm | 101 | 295 | 34.2% | cbioportal |
| 4 | ARID1A | Ssm | 90 | 295 | 30.5% | cbioportal |
| 5 | LRP1B | Ssm | 78 | 295 | 26.4% | cbioportal |
| 6 | SYNE1 | Ssm | 76 | 295 | 25.8% | cbioportal |
| 7 | FAT4 | Ssm | 70 | 295 | 23.7% | cbioportal |
| 8 | CSMD3 | Ssm | 68 | 295 | 23.1% | cbioportal |
| 9 | PCLO | Ssm | 67 | 295 | 22.7% | cbioportal |
| 10 | HMCN1 | Ssm | 66 | 295 | 22.4% | cbioportal |
| 11 | CSMD1 | Ssm | 65 | 295 | 22% | cbioportal |
| 12 | KMT2D | Ssm | 65 | 295 | 22% | cbioportal |
| 13 | FLG | Ssm | 62 | 295 | 21% | cbioportal |
| 14 | RYR2 | Ssm | 59 | 295 | 20% | cbioportal |
| 15 | PIK3CA | Ssm | 57 | 295 | 19.3% | cbioportal |
| 16 | SPTA1 | Ssm | 57 | 295 | 19.3% | cbioportal |
| 18 | FAT3 | Ssm | 56 | 295 | 19% | cbioportal |
| 17 | DNAH5 | Ssm | 56 | 295 | 19% | cbioportal |
| 19 | OBSCN | Ssm | 55 | 295 | 18.6% | cbioportal |
| 20 | ZFHX4 | Ssm | 53 | 295 | 18% | cbioportal |
| 21 | RYR3 | Ssm | 50 | 295 | 16.9% | cbioportal |
| 22 | PCDH15 | Ssm | 49 | 295 | 16.6% | cbioportal |
| 23 | RNF43 | Ssm | 49 | 295 | 16.6% | cbioportal |
| 24 | ADGRV1 | Ssm | 48 | 295 | 16.3% | cbioportal |
| 25 | PLEC | Ssm | 48 | 295 | 16.3% | cbioportal |
| 27 | SACS | Ssm | 47 | 295 | 15.9% | cbioportal |
| 26 | DMD | Ssm | 47 | 295 | 15.9% | cbioportal |
| 30 | TSPOAP1 | Ssm | 46 | 295 | 15.6% | cbioportal |
| 32 | XIRP2 | Ssm | 46 | 295 | 15.6% | cbioportal |
| 31 | USH2A | Ssm | 46 | 295 | 15.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13