Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
109 cases with simple somatic mutation data · 109 cases total · 2026-01-05 · mapped to Bladder Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 63 |
| 109 |
| 57.8% |
| cbioportal |
| 2 | KDM6A | Ssm | 45 | 109 | 41.3% | cbioportal |
| 3 | KMT2D | Ssm | 34 | 109 | 31.2% | cbioportal |
| 4 | ARID1A | Ssm | 31 | 109 | 28.4% | cbioportal |
| 6 | RB1 | Ssm | 25 | 109 | 22.9% | cbioportal |
| 5 | PIK3CA | Ssm | 25 | 109 | 22.9% | cbioportal |
| 7 | FGFR3 | Ssm | 21 | 109 | 19.3% | cbioportal |
| 8 | EP300 | Ssm | 17 | 109 | 15.6% | cbioportal |
| 9 | STAG2 | Ssm | 16 | 109 | 14.7% | cbioportal |
| 11 | KMT2C | Ssm | 15 | 109 | 13.8% | cbioportal |
| 10 | CREBBP | Ssm | 15 | 109 | 13.8% | cbioportal |
| 12 | ERBB3 | Ssm | 14 | 109 | 12.8% | cbioportal |
| 14 | ERBB2 | Ssm | 13 | 109 | 11.9% | cbioportal |
| 13 | CDKN1A | Ssm | 13 | 109 | 11.9% | cbioportal |
| 17 | NF1 | Ssm | 12 | 109 | 11% | cbioportal |
| 16 | KMT2A | Ssm | 12 | 109 | 11% | cbioportal |
| 15 | FAT1 | Ssm | 12 | 109 | 11% | cbioportal |
| 18 | RICTOR | Ssm | 10 | 109 | 9.2% | cbioportal |
| 19 | SMARCA4 | Ssm | 10 | 109 | 9.2% | cbioportal |
| 20 | ATM | Ssm | 9 | 109 | 8.3% | cbioportal |
| 21 | ATRX | Ssm | 8 | 109 | 7.3% | cbioportal |
| 22 | NOTCH1 | Ssm | 8 | 109 | 7.3% | cbioportal |
| 23 | TERT | Ssm | 8 | 109 | 7.3% | cbioportal |
| 28 | NOTCH4 | Ssm | 7 | 109 | 6.4% | cbioportal |
| 24 | BRCA1 | Ssm | 7 | 109 | 6.4% | cbioportal |
| 29 | PIK3CG | Ssm | 7 | 109 | 6.4% | cbioportal |
| 25 | CDK12 | Ssm | 7 | 109 | 6.4% | cbioportal |
| 26 | NFKB1 | Ssm | 7 | 109 | 6.4% | cbioportal |
| 27 | NOTCH3 | Ssm | 7 | 109 | 6.4% | cbioportal |
| 32 | ETV6 | Ssm | 6 | 109 | 5.5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-05